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Mendeley readers
Attention Score in Context
| Title |
A focus on the synapse for neuroprotection in Alzheimer disease and other dementias
|
|---|---|
| Published in |
Neurology, October 2004
|
| DOI | 10.1212/01.wnl.0000140626.48118.0a |
| Pubmed ID | |
| Authors |
Paul Coleman, Howard Federoff, Roger Kurlan |
| Abstract |
Synaptic dysfunction and failure are processes that occur early in Alzheimer disease (AD) and are important targets for protective treatments to slow AD progression and preserve cognitive and functional abilities. Synaptic loss is the best current pathologic correlate of cognitive decline, and synaptic dysfunction is evident long before synapses and neurons are lost. Once synaptic function fails, even in the setting of surviving neurons, there may be little chance of effectively interfering with the disease process. This review emphasizes the importance of preserving synaptic structure and function (i.e., "synaptoprotection") in AD. Such "synaptoprotective" therapy will probably need to be administered at a critical early time point, perhaps years before onset of clinical symptoms. |
Mendeley readers
The data shown below were compiled from readership statistics for 154 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 2% |
| Germany | 1 | <1% |
| Italy | 1 | <1% |
| United Kingdom | 1 | <1% |
| Austria | 1 | <1% |
| Spain | 1 | <1% |
| Poland | 1 | <1% |
| Unknown | 145 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 36 | 23% |
| Student > Ph. D. Student | 31 | 20% |
| Student > Bachelor | 13 | 8% |
| Student > Master | 13 | 8% |
| Professor > Associate Professor | 10 | 6% |
| Other | 27 | 18% |
| Unknown | 24 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 42 | 27% |
| Neuroscience | 30 | 19% |
| Medicine and Dentistry | 18 | 12% |
| Biochemistry, Genetics and Molecular Biology | 9 | 6% |
| Psychology | 7 | 5% |
| Other | 14 | 9% |
| Unknown | 34 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 August 2020.
All research outputs
#8,535,684
of 25,377,790 outputs
Outputs from Neurology
#11,123
of 21,010 outputs
Outputs of similar age
#24,705
of 75,892 outputs
Outputs of similar age from Neurology
#47
of 104 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 21,010 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 23.7. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 75,892 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 104 others from the same source and published within six weeks on either side of this one. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.