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Mendeley readers
Attention Score in Context
| Title |
Prevalence of Anderson-Fabry Disease in Male Patients With Late Onset Hypertrophic Cardiomyopathy
|
|---|---|
| Published in |
Circulation, March 2002
|
| DOI | 10.1161/01.cir.0000012626.81324.38 |
| Pubmed ID | |
| Authors |
B. Sachdev, T. Takenaka, H. Teraguchi, C. Tei, P. Lee, W.J. McKenna, P.M. Elliott |
| Abstract |
Although studies have suggested that "late-onset" hypertrophic cardiomyopathy (HCM) may be caused by sarcomeric protein gene mutations, the cause of HCM in the majority of patients is unknown. This study determined the prevalence of a potentially treatable cause of hypertrophy, Anderson-Fabry disease, in a HCM referral population. Plasma alpha-galactosidase A (alpha-Gal) was measured in 79 men with HCM who were diagnosed at > or =40 years of age (52.9+/-7.7 years; range, 40-71 years) and in 74 men who were diagnosed at <40 years (25.9+/-9.2 years; range, 8-39 years). Five patients (6.3%) with late-onset disease and 1 patient (1.4%) diagnosed at <40 years had low alpha-Gal activity. Of these 6 patients, 3 had angina, 4 were in New York Heart Association class 2, 5 had palpitations, and 2 had a history of syncope. Hypertrophy was concentric in 5 patients and asymmetric in 1 patient. One patient had left ventricular outflow tract obstruction. All patients with low alpha-Gal activity had alpha-Gal gene mutations. Anderson-Fabry disease should be considered in all cases of unexplained hypertrophy. Its recognition is important given the advent of specific replacement enzyme therapy. |
Mendeley readers
The data shown below were compiled from readership statistics for 178 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Colombia | 3 | 2% |
| Spain | 2 | 1% |
| United Kingdom | 2 | 1% |
| Italy | 1 | <1% |
| Ukraine | 1 | <1% |
| Japan | 1 | <1% |
| Unknown | 168 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 33 | 19% |
| Student > Ph. D. Student | 23 | 13% |
| Other | 18 | 10% |
| Student > Master | 17 | 10% |
| Student > Bachelor | 17 | 10% |
| Other | 40 | 22% |
| Unknown | 30 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 96 | 54% |
| Biochemistry, Genetics and Molecular Biology | 16 | 9% |
| Agricultural and Biological Sciences | 13 | 7% |
| Economics, Econometrics and Finance | 3 | 2% |
| Business, Management and Accounting | 2 | 1% |
| Other | 8 | 4% |
| Unknown | 40 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 September 2006.
All research outputs
#7,563,204
of 23,070,218 outputs
Outputs from Circulation
#11,191
of 19,752 outputs
Outputs of similar age
#39,910
of 121,352 outputs
Outputs of similar age from Circulation
#82
of 152 outputs
Altmetric has tracked 23,070,218 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 19,752 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 29.5. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 121,352 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 152 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.