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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Consensus nomenclature for CD8+ T cell phenotypes in cancer
|
|---|---|
| Published in |
OncoImmunology, February 2015
|
| DOI | 10.1080/2162402x.2014.998538 |
| Pubmed ID | |
| Authors |
Lionel Apetoh, Mark J. Smyth, Charles G. Drake, Jean-Pierre Abastado, Ron N. Apte, Maha Ayyoub, Jean-Yves Blay, Marc Bonneville, Lisa H. Butterfield, Anne Caignard, Chiara Castelli, Federica Cavallo, Esteban Celis, Lieping Chen, Mario P. Colombo, Begoña Comin-Anduix, Georges Coukos, Madhav V. Dhodapkar, Glenn Dranoff, Ian H. Frazer, Wolf-Hervé Fridman, Dmitry I. Gabrilovich, Eli Gilboa, Sacha Gnjatic, Dirk Jäger, Pawel Kalinski, Howard L. Kaufman, Rolf Kiessling, John Kirkwood, Alexander Knuth, Roland Liblau, Michael T. Lotze, Enrico Lugli, Francesco Marincola, Ignacio Melero, Cornelis J. Melief, Thorsten R. Mempel, Elizabeth A. Mittendorf, Kunle Odun, Willem W. Overwijk, Anna Karolina Palucka, Giorgio Parmiani, Antoni Ribas, Pedro Romero, Robert D. Schreiber, Gerold Schuler, Pramod K. Srivastava, Eric Tartour, Danila Valmori, Sjoerd H. van der Burg, Pierre van der Bruggen, Benoît J. van den Eynde, Ena Wang, Weiping Zou, Theresa L. Whiteside, Daniel E. Speiser, Drew M. Pardoll, Nicholas P. Restifo, Ana C. Anderson |
| Abstract |
Whereas preclinical investigations and clinical studies have established that CD8(+) T cells can profoundly affect cancer progression, the underlying mechanisms are still elusive. Challenging the prevalent view that the beneficial effect of CD8(+) T cells in cancer is solely attributable to their cytotoxic activity, several reports have indicated that the ability of CD8(+) T cells to promote tumor regression is dependent on their cytokine secretion profile and their ability to self-renew. Evidence has also shown that the tumor microenvironment can disarm CD8(+) T cell immunity, leading to the emergence of dysfunctional CD8(+) T cells. The existence of different types of CD8(+) T cells in cancer calls for a more precise definition of the CD8(+) T cell immune phenotypes in cancer and the abandonment of the generic terms "pro-tumor" and "antitumor." Based on recent studies investigating the functions of CD8(+) T cells in cancer, we here propose some guidelines to precisely define the functional states of CD8(+) T cells in cancer. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 17% |
| Unknown | 5 | 83% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 83% |
| Scientists | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 231 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | <1% |
| Australia | 1 | <1% |
| Czechia | 1 | <1% |
| Spain | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 226 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 55 | 24% |
| Student > Ph. D. Student | 41 | 18% |
| Student > Master | 29 | 13% |
| Professor | 15 | 6% |
| Student > Doctoral Student | 14 | 6% |
| Other | 37 | 16% |
| Unknown | 40 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 55 | 24% |
| Immunology and Microbiology | 53 | 23% |
| Medicine and Dentistry | 39 | 17% |
| Biochemistry, Genetics and Molecular Biology | 22 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 3% |
| Other | 10 | 4% |
| Unknown | 46 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2023.
All research outputs
#1,930,269
of 25,377,790 outputs
Outputs from OncoImmunology
#92
of 2,178 outputs
Outputs of similar age
#23,789
of 270,081 outputs
Outputs of similar age from OncoImmunology
#5
of 114 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,178 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 270,081 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 114 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.