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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Vancomycin-associated nephrotoxicity: A meta-analysis of administration by continuous versus intermittent infusion
|
|---|---|
| Published in |
International Journal of Antimicrobial Agents, June 2015
|
| DOI | 10.1016/j.ijantimicag.2015.04.013 |
| Pubmed ID | |
| Authors |
Timothy Hanrahan, Tony Whitehouse, Jeffrey Lipman, Jason A. Roberts |
| Abstract |
Vancomycin is a glycopeptide antibiotic widely used in the management of meticillin-resistant Staphylococcus aureus (MRSA). Guidelines currently recommend vancomycin be administered by intermittent infusion, despite recent research suggesting that continuous infusion (CI) may be associated with lower rates of vancomycin-associated nephrotoxicity. In 2012, Cataldo et al. presented a meta-analysis supporting the use of CI. Here we present an updated meta-analysis, inclusive of a recently published large-scale retrospective study. PubMed, EMBASE and Cochrane Reviews databases were searched using the keywords 'vancomycin' and 'continuous' or 'intermittent' or 'infusion' or 'discontinuous' or 'administration'. Seven studies were included in the final analysis. Using a random-effects model, a non-significant trend of reduced nephrotoxicity in those who received vancomycin by CI (risk ratio=0.799, 95% confidence interval 0.523-1.220; P=0.299) was identified. A large, randomised controlled trial is necessary to confirm these results. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 67% |
| Japan | 1 | 17% |
| Unknown | 1 | 17% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 67% |
| Practitioners (doctors, other healthcare professionals) | 1 | 17% |
| Scientists | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 1% |
| Unknown | 73 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 12 | 16% |
| Other | 10 | 14% |
| Researcher | 7 | 9% |
| Student > Ph. D. Student | 6 | 8% |
| Student > Master | 6 | 8% |
| Other | 15 | 20% |
| Unknown | 18 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 31 | 42% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 9% |
| Nursing and Health Professions | 2 | 3% |
| Biochemistry, Genetics and Molecular Biology | 2 | 3% |
| Chemistry | 2 | 3% |
| Other | 8 | 11% |
| Unknown | 22 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 October 2019.
All research outputs
#8,163,460
of 25,374,647 outputs
Outputs from International Journal of Antimicrobial Agents
#1,087
of 3,029 outputs
Outputs of similar age
#91,213
of 280,349 outputs
Outputs of similar age from International Journal of Antimicrobial Agents
#13
of 53 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 3,029 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.3. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,349 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.