Title |
Epigenome data release: a participant-centered approach to privacy protection
|
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Published in |
Genome Biology, July 2015
|
DOI | 10.1186/s13059-015-0723-0 |
Pubmed ID | |
Authors |
Stephanie O. M. Dyke, Warren A. Cheung, Yann Joly, Ole Ammerpohl, Pavlo Lutsik, Mark A. Rothstein, Maxime Caron, Stephan Busche, Guillaume Bourque, Lars Rönnblom, Paul Flicek, Stephan Beck, Martin Hirst, Henk Stunnenberg, Reiner Siebert, Jörn Walter, Tomi Pastinen |
Abstract |
Large-scale epigenome mapping by the NIH Roadmap Epigenomics Project, the ENCODE Consortium and the International Human Epigenome Consortium (IHEC) produces genome-wide DNA methylation data at one base-pair resolution. We examine how such data can be made open-access while balancing appropriate interpretation and genomic privacy. We propose guidelines for data release that both reduce ambiguity in the interpretation of open-access data and limit immediate access to genetic variation data that are made available through controlled access. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 15% |
Canada | 4 | 15% |
United Kingdom | 4 | 15% |
Australia | 1 | 4% |
Sao Tome and Principe | 1 | 4% |
Korea, Republic of | 1 | 4% |
Spain | 1 | 4% |
Belgium | 1 | 4% |
Unknown | 10 | 37% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 20 | 74% |
Scientists | 4 | 15% |
Practitioners (doctors, other healthcare professionals) | 2 | 7% |
Science communicators (journalists, bloggers, editors) | 1 | 4% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 2% |
Netherlands | 1 | 2% |
Germany | 1 | 2% |
Switzerland | 1 | 2% |
Unknown | 56 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 17 | 28% |
Student > Ph. D. Student | 10 | 17% |
Student > Bachelor | 7 | 12% |
Student > Doctoral Student | 4 | 7% |
Other | 4 | 7% |
Other | 13 | 22% |
Unknown | 5 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 18 | 30% |
Agricultural and Biological Sciences | 14 | 23% |
Computer Science | 8 | 13% |
Medicine and Dentistry | 5 | 8% |
Nursing and Health Professions | 1 | 2% |
Other | 4 | 7% |
Unknown | 10 | 17% |