| Title |
Cryptococcal Meningitis: Diagnosis and Management Update
|
|---|---|
| Published in |
Current Tropical Medicine Reports, April 2015
|
| DOI | 10.1007/s40475-015-0046-y |
| Pubmed ID | |
| Authors |
Mahsa Abassi, David R. Boulware, Joshua Rhein |
| Abstract |
Recent advances in the diagnosis and management of cryptococcal meningitis are promising and have been improving long-term survival. Point of care testing has made diagnosing cryptococcal meningitis rapid, practical, and affordable. Targeted screening and treatment programs for cryptococcal antigenemia are a cost effective method for reducing early mortality on antiretroviral therapy (ART). Optimal initial management with amphotericin and flucytosine improves survival against alternative therapies, although amphotericin is difficult to administer and flucytosine is not available in middle or low income countries, where cryptococcal meningitis is most prevalent. Controlling increased intracranial pressure with serial therapeutic lumbar punctures has a proven survival benefit. Delaying ART initiation for 4 weeks after the diagnosis of cryptococcal meningitis is associated with improved survival. Fortunately, new approaches have been leading the way toward improving care for cryptococcal meningitis patients. New trials utilizing different combinations of antifungal therapy are reviewed, and we summarize the efficacy of different regimens. |
X Demographics
The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 33% |
| United States | 2 | 22% |
| Ecuador | 1 | 11% |
| Denmark | 1 | 11% |
| Unknown | 2 | 22% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 56% |
| Practitioners (doctors, other healthcare professionals) | 3 | 33% |
| Scientists | 1 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 305 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Tanzania, United Republic of | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 303 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 48 | 16% |
| Student > Master | 39 | 13% |
| Student > Postgraduate | 28 | 9% |
| Researcher | 22 | 7% |
| Student > Ph. D. Student | 22 | 7% |
| Other | 64 | 21% |
| Unknown | 82 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 107 | 35% |
| Pharmacology, Toxicology and Pharmaceutical Science | 21 | 7% |
| Nursing and Health Professions | 17 | 6% |
| Biochemistry, Genetics and Molecular Biology | 15 | 5% |
| Immunology and Microbiology | 14 | 5% |
| Other | 39 | 13% |
| Unknown | 92 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 27. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 August 2023.
All research outputs
#1,377,717
of 24,588,574 outputs
Outputs from Current Tropical Medicine Reports
#10
of 144 outputs
Outputs of similar age
#17,416
of 270,328 outputs
Outputs of similar age from Current Tropical Medicine Reports
#3
of 5 outputs
Altmetric has tracked 24,588,574 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 144 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 270,328 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.