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A probable prehistoric case of meningococcal disease from San Francisco Bay: Next generation sequencing of Neisseria meningitidis from dental calculus and osteological evidence

Overview of attention for article published in International Journal of Paleopathology, May 2018
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Title
A probable prehistoric case of meningococcal disease from San Francisco Bay: Next generation sequencing of Neisseria meningitidis from dental calculus and osteological evidence
Published in
International Journal of Paleopathology, May 2018
DOI 10.1016/j.ijpp.2018.05.001
Pubmed ID
Authors

Jelmer W. Eerkens, Ruth V. Nichols, Gemma G.R. Murray, Katherine Perez, Engel Murga, Phil Kaijankoski, Jeffrey S. Rosenthal, Laurel Engbring, Beth Shapiro

Abstract

Next Generation Sequencing (NGS) of ancient dental calculus samples from a prehistoric site in San Francisco Bay, CA-SCL-919, reveals a wide range of potentially pathogenic bacteria. One older adult woman, in particular, had high levels of Neisseria meningitidis and low levels of Haemophilus influenzae, species that were not observed in the calculus from three other individuals. Combined with the presence of incipient endocranial lesions and pronounced meningeal grooves, we interpret this as an ancient case of meningococcal disease. This disease afflicts millions around the globe today, but little is known about its (pre)history. With additional sampling, we suggest NGS of calculus offers an exciting new window into the evolutionary history of these bacterial species and their interactions with humans.

X Demographics

X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 40 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 28%
Student > Bachelor 6 15%
Researcher 4 10%
Student > Master 4 10%
Professor 3 8%
Other 4 10%
Unknown 8 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 20%
Biochemistry, Genetics and Molecular Biology 7 18%
Medicine and Dentistry 4 10%
Arts and Humanities 3 8%
Immunology and Microbiology 2 5%
Other 4 10%
Unknown 12 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 May 2019.
All research outputs
#14,920,631
of 25,382,440 outputs
Outputs from International Journal of Paleopathology
#269
of 454 outputs
Outputs of similar age
#177,805
of 344,607 outputs
Outputs of similar age from International Journal of Paleopathology
#8
of 10 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 454 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.0. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 344,607 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.