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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Anxiety is related to indices of cortical maturation in typically developing children and adolescents
|
|---|---|
| Published in |
Brain Structure and Function, July 2015
|
| DOI | 10.1007/s00429-015-1085-9 |
| Pubmed ID | |
| Authors |
Erik Newman, Wesley K. Thompson, Hauke Bartsch, Donald J. Hagler, Chi-Hua Chen, Timothy T. Brown, Joshua M. Kuperman, Connor McCabe, Yoonho Chung, Ondrej Libiger, Natacha Akshoomoff, Cinnamon S. Bloss, B. J. Casey, Linda Chang, Thomas M. Ernst, Jean A. Frazier, Jeffrey R. Gruen, David N. Kennedy, Sarah S. Murray, Elizabeth R. Sowell, Nicholas Schork, Tal Kenet, Walter E. Kaufmann, Stewart Mostofsky, David G. Amaral, Anders M. Dale, Terry L. Jernigan |
| Abstract |
Anxiety is a risk factor for many adverse neuropsychiatric and socioeconomic outcomes, and has been linked to functional and structural changes in the ventromedial prefrontal cortex (VMPFC). However, the nature of these differences, as well as how they develop in children and adolescents, remains poorly understood. More effective interventions to minimize the negative consequences of anxiety require better understanding of its neurobiology in children. Recent research suggests that structural imaging studies may benefit from clearly delineating between cortical surface area and thickness when examining these associations, as these distinct cortical phenotypes are influenced by different cellular mechanisms and genetic factors. The present study examined relationships between cortical surface area and thickness of the VMPFC and a self-report measure of anxiety (SCARED-R) in 287 youths aged 7-20 years from the Pediatric Imaging, Neurocognition, and Genetics (PING) study. Age and gender interactions were examined for significant associations in order to test for developmental differences. Cortical surface area and thickness were also examined simultaneously to determine whether they contribute independently to the prediction of anxiety. Anxiety was negatively associated with relative cortical surface area of the VMPFC as well as with global cortical thickness, but these associations diminished with age. The two cortical phenotypes contributed additively to the prediction of anxiety. These findings suggest that higher anxiety in children may be characterized by both delayed expansion of the VMPFC and an altered trajectory of global cortical thinning. Further longitudinal studies will be needed to confirm these findings. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 102 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 19 | 19% |
| Student > Ph. D. Student | 13 | 13% |
| Student > Master | 12 | 12% |
| Student > Doctoral Student | 10 | 10% |
| Professor | 8 | 8% |
| Other | 19 | 19% |
| Unknown | 21 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 31 | 30% |
| Neuroscience | 16 | 16% |
| Medicine and Dentistry | 10 | 10% |
| Agricultural and Biological Sciences | 5 | 5% |
| Social Sciences | 3 | 3% |
| Other | 7 | 7% |
| Unknown | 30 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 September 2017.
All research outputs
#19,015,393
of 24,217,893 outputs
Outputs from Brain Structure and Function
#1,150
of 1,725 outputs
Outputs of similar age
#161,884
of 238,572 outputs
Outputs of similar age from Brain Structure and Function
#15
of 20 outputs
Altmetric has tracked 24,217,893 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,725 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 238,572 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.