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Acute effects of nicotine administration during prospective memory, an event related fMRI study

Overview of attention for article published in Neuropsychologia, April 2011
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Title
Acute effects of nicotine administration during prospective memory, an event related fMRI study
Published in
Neuropsychologia, April 2011
DOI 10.1016/j.neuropsychologia.2011.04.009
Pubmed ID
Authors

Jennifer Rusted, Torsten Ruest, Marcus A. Gray

Abstract

We previously demonstrated that stimulating neuronal nicotinic acetylcholine receptors modulates prospective memory (PM), the ability to remember and implement a prior intention. Here we used fMRI to explore the neuronal correlates of acute nicotinic (1mg) modulation during PM, employing a double blind, valence-matched placebo-controlled design, and a solely event-related analysis. Eight healthy adults completed on two occasions (1 week washout) a simple attentional task containing infrequent PM trials. PM activated bilateral parietal, prefrontal (BA10) and anterior cingulate, and deactivated genual cingulate and medial prefrontal regions. Further, acute nicotine administration decreased activity within a largely overlapping right parietal region. This data validates a purely event-related approach to exploring PM, and suggests procholinergic modulation of PM by parietal rather than BA10/frontal regions.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 3 4%
Germany 2 3%
Unknown 66 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 18%
Student > Ph. D. Student 13 18%
Student > Bachelor 8 11%
Student > Doctoral Student 5 7%
Student > Postgraduate 5 7%
Other 18 25%
Unknown 9 13%
Readers by discipline Count As %
Psychology 28 39%
Neuroscience 9 13%
Agricultural and Biological Sciences 8 11%
Medicine and Dentistry 6 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 1%
Other 7 10%
Unknown 12 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 October 2011.
All research outputs
#17,286,379
of 25,374,647 outputs
Outputs from Neuropsychologia
#2,968
of 4,173 outputs
Outputs of similar age
#86,309
of 109,779 outputs
Outputs of similar age from Neuropsychologia
#20
of 36 outputs
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