Title |
Quickening: Translational design of resorbable synthetic vascular grafts
|
---|---|
Published in |
Clinical Materials, May 2018
|
DOI | 10.1016/j.biomaterials.2018.05.006 |
Pubmed ID | |
Authors |
Chelsea E T Stowell, Yadong Wang |
Abstract |
Traditional tissue-engineered vascular grafts have yet to gain wide clinical use. The difficulty of scaling production of these cell- or biologic-based products has hindered commercialization. In situ tissue engineering bypasses such logistical challenges by using acellular resorbable scaffolds. Upon implant, the scaffolds become remodeled by host cells. This review describes the scientific and translational advantages of acellular, synthetic vascular grafts. It surveys in vivo results obtained with acellular synthetics over their fifty years of technological development. Finally, it discusses emerging principles, highlights strategic considerations for designers, and identifies questions needing additional research. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 38% |
Australia | 2 | 25% |
United Kingdom | 1 | 13% |
Ireland | 1 | 13% |
Tunisia | 1 | 13% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 63% |
Scientists | 2 | 25% |
Science communicators (journalists, bloggers, editors) | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 90 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 22 | 24% |
Researcher | 11 | 12% |
Student > Master | 11 | 12% |
Student > Bachelor | 9 | 10% |
Professor > Associate Professor | 4 | 4% |
Other | 7 | 8% |
Unknown | 26 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Engineering | 21 | 23% |
Medicine and Dentistry | 11 | 12% |
Materials Science | 7 | 8% |
Agricultural and Biological Sciences | 6 | 7% |
Biochemistry, Genetics and Molecular Biology | 3 | 3% |
Other | 6 | 7% |
Unknown | 36 | 40% |