Title |
Non-contact scanning diffuse correlation tomography system for three-dimensional blood flow imaging in a murine bone graft model
|
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Published in |
Biomedical Optics Express, June 2015
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DOI | 10.1364/boe.6.002695 |
Pubmed ID | |
Authors |
Songfeng Han, Johannes Johansson, Miguel Mireles, Ashley R. Proctor, Michael D. Hoffman, Joseph B. Vella, Danielle S. W. Benoit, Turgut Durduran, Regine Choe |
Abstract |
A non-contact galvanometer-based optical scanning system for diffuse correlation tomography was developed for monitoring bone graft healing in a murine femur model. A linear image reconstruction algorithm for diffuse correlation tomography was tested using finite-element method based simulated data and experimental data from a femur or a tube suspended in a homogeneous liquid phantom. Finally, the non-contact system was utilized to monitor in vivo blood flow changes prior to and one week after bone graft transplantation within murine femurs. Localized blood flow changes were observed in three mice, demonstrating a potential for quantification of longitudinal blood flow associated with bone graft healing. |
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Unknown | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
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Unknown | 38 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 11 | 28% |
Researcher | 5 | 13% |
Student > Postgraduate | 5 | 13% |
Student > Master | 4 | 10% |
Professor > Associate Professor | 3 | 8% |
Other | 6 | 15% |
Unknown | 6 | 15% |
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Unspecified | 1 | 3% |
Other | 0 | 0% |
Unknown | 6 | 15% |