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Oxidation products of hyperforin from Hypericum perforatum

Overview of attention for article published in Phytochemistry, November 1998
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2 patents

Citations

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26 Mendeley
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Title
Oxidation products of hyperforin from Hypericum perforatum
Published in
Phytochemistry, November 1998
DOI 10.1016/s0031-9422(97)00903-5
Pubmed ID
Authors

Snežana Trifunović, Vlatka Vajs, Slobodan Macura, Nenad Juranić, Zoltan Djarmati, Ratko Jankov, Slobodan Milosavljević

Abstract

The isolation of two oxidation products of hyperforin from the aerial parts of Hypericum perforatum and their structure determination by means of 2D NMR methods is reported. The products had the same 1-(2-methyl-1-oxopropyl)-2,12-dioxo-3,10 beta-bis(3-methyl-2-butenyl)-11 beta-methyl-11 alpha-(4-methyl-3-pentenyl)-5-oxatricyclo[6.3.1.0(4,8)]-3-dodec ene skeleton. In addition, one of them, with the same number of carbons as hyperforin (C35H52O5), contained a 1-methyl-l-hydroxyethyl group in the 6 beta-position, whereas the other compound (a hemiacetal, C32H46O5), presumably a degradation product of hyperforin, exhibited a 6-hydroxy function. The latter was an inseparable mixture of 6 alpha- and 6 beta-hydroxy epimers undergoing (according to phase sensitive NOESY) mutual interconversion.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 31%
Student > Master 6 23%
Student > Ph. D. Student 4 15%
Professor 2 8%
Student > Doctoral Student 1 4%
Other 2 8%
Unknown 3 12%
Readers by discipline Count As %
Chemistry 7 27%
Agricultural and Biological Sciences 5 19%
Biochemistry, Genetics and Molecular Biology 3 12%
Pharmacology, Toxicology and Pharmaceutical Science 3 12%
Medicine and Dentistry 1 4%
Other 0 0%
Unknown 7 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 May 2001.
All research outputs
#8,534,976
of 25,374,647 outputs
Outputs from Phytochemistry
#1,629
of 6,216 outputs
Outputs of similar age
#12,885
of 41,613 outputs
Outputs of similar age from Phytochemistry
#21
of 60 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,216 research outputs from this source. They receive a mean Attention Score of 4.2. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 41,613 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.