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Low risk of seroconversion or clinical disease in humans after a bite by an Anaplasma phagocytophilum-infected tick

Overview of attention for article published in Ticks and Tick-borne Diseases, July 2015
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  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (56th percentile)

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Title
Low risk of seroconversion or clinical disease in humans after a bite by an Anaplasma phagocytophilum-infected tick
Published in
Ticks and Tick-borne Diseases, July 2015
DOI 10.1016/j.ttbdis.2015.07.005
Pubmed ID
Authors

Anna J. Henningsson, Peter Wilhelmsson, Paula Gyllemark, Monika Kozak, Andreas Matussek, Dag Nyman, Christina Ekerfelt, Per-Eric Lindgren, Pia Forsberg

Abstract

The risk of contracting human granulocytic anaplasmosis (HGA) after a tick bite is mainly unknown. In this study we investigated the clinical and serological response in 30 humans bitten by ticks positive for Anaplasma phagocytophilum (Group A), 30 humans bitten by Borrelia burgdorferi sensu lato (s.l.)-positive ticks (Group B), and 30 humans bitten by ticks negative for both A. phagocytophilum and B. burgdorferi s.l. (Group C). Ticks, blood samples and questionnaires were collected from tick-bitten humans at 34 primary healthcare centres in Sweden and in the Åland Islands, Finland, at the time of the tick bite and after three months. A total of 2553 ticks detached from humans in 2007-2009 were analyzed by polymerase chain reaction, and 31 (1.2%) were positive for A. phagocytophilum, 556 (21.8%) were positive for B. burgdorferi s.l., and eight (0.3%) were co-infected by A. phagocytophilum and B. burgdorferi s.l. The overall prevalence of Anaplasma IgG antibodies in the included participants (n=90) was 17%, and there was no significant difference between the groups A-C. Only one of the participants (in Group C) showed a four-fold increase of IgG antibodies against A. phagocytophilum at the three-month follow-up, but reported no symptoms. The frequency of reported symptoms did not differ between groups A-C, and was unrelated to the findings of A. phagocytophilum and B. burgdorferi s.l. in the detached ticks. We conclude that the risk for HGA or asymptomatic seroconversion after a tick bite in Sweden or in the Åland Islands is low, even if the tick is infected by A. phagocytophilum.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Unknown 52 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 15%
Researcher 7 13%
Student > Bachelor 5 9%
Librarian 4 8%
Student > Master 4 8%
Other 8 15%
Unknown 17 32%
Readers by discipline Count As %
Medicine and Dentistry 9 17%
Veterinary Science and Veterinary Medicine 7 13%
Agricultural and Biological Sciences 7 13%
Philosophy 2 4%
Neuroscience 2 4%
Other 8 15%
Unknown 18 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 September 2018.
All research outputs
#14,599,900
of 25,373,627 outputs
Outputs from Ticks and Tick-borne Diseases
#587
of 1,883 outputs
Outputs of similar age
#125,885
of 276,131 outputs
Outputs of similar age from Ticks and Tick-borne Diseases
#13
of 37 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,883 research outputs from this source. They receive a mean Attention Score of 4.5. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,131 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.