| Title |
Regulation of mitophagy in ischemic brain injury
|
|---|---|
| Published in |
Neuroscience Bulletin, July 2015
|
| DOI | 10.1007/s12264-015-1544-6 |
| Pubmed ID | |
| Authors |
Yang Yuan, Xiangnan Zhang, Yanrong Zheng, Zhong Chen |
| Abstract |
The selective degradation of damaged or excessive mitochondria by autophagy is termed mitophagy. Mitophagy is crucial for mitochondrial quality control and has been implicated in several neurodegenerative disorders as well as in ischemic brain injury. Emerging evidence suggested that the role of mitophagy in cerebral ischemia may depend on different pathological processes. In particular, a neuroprotective role of mitophagy has been proposed, and the regulation of mitophagy seems to be important in cell survival. For these reasons, extensive investigations aimed to profi le the mitophagy process and its underlying molecular mechanisms have been executed in recent years. In this review, we summarize the current knowledge regarding the mitophagy process and its role in cerebral ischemia, and focus on the pathological events and molecules that regulate mitophagy in ischemic brain injury. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 28 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 6 | 21% |
| Student > Master | 6 | 21% |
| Student > Bachelor | 3 | 11% |
| Other | 2 | 7% |
| Researcher | 2 | 7% |
| Other | 3 | 11% |
| Unknown | 6 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 5 | 18% |
| Biochemistry, Genetics and Molecular Biology | 4 | 14% |
| Neuroscience | 4 | 14% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 11% |
| Medicine and Dentistry | 2 | 7% |
| Other | 3 | 11% |
| Unknown | 7 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 July 2015.
All research outputs
#3,067,151
of 22,818,766 outputs
Outputs from Neuroscience Bulletin
#82
of 770 outputs
Outputs of similar age
#41,041
of 263,394 outputs
Outputs of similar age from Neuroscience Bulletin
#5
of 22 outputs
Altmetric has tracked 22,818,766 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 770 research outputs from this source. They receive a mean Attention Score of 4.0. This one has done well, scoring higher than 88% of its peers.
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We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.