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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma
|
|---|---|
| Published in |
Nature Genetics, August 2015
|
| DOI | 10.1038/ng.3373 |
| Pubmed ID | |
| Authors |
Matthew H Law, D Timothy Bishop, Jeffrey E Lee, Myriam Brossard, Nicholas G Martin, Eric K Moses, Fengju Song, Jennifer H Barrett, Rajiv Kumar, Douglas F Easton, Paul D P Pharoah, Anthony J Swerdlow, Katerina P Kypreou, John C Taylor, Mark Harland, Juliette Randerson-Moor, Lars A Akslen, Per A Andresen, Marie-Françoise Avril, Esther Azizi, Giovanna Bianchi Scarrà, Kevin M Brown, Tadeusz Dȩbniak, David L Duffy, David E Elder, Shenying Fang, Eitan Friedman, Pilar Galan, Paola Ghiorzo, Elizabeth M Gillanders, Alisa M Goldstein, Nelleke A Gruis, Johan Hansson, Per Helsing, Marko Hočevar, Veronica Höiom, Christian Ingvar, Peter A Kanetsky, Wei V Chen, Maria Teresa Landi, Julie Lang, G Mark Lathrop, Jan Lubiński, Rona M Mackie, Graham J Mann, Anders Molven, Grant W Montgomery, Srdjan Novaković, Håkan Olsson, Susana Puig, Joan Anton Puig-Butille, Abrar A Qureshi, Graham L Radford-Smith, Nienke van der Stoep, Remco van Doorn, David C Whiteman, Jamie E Craig, Dirk Schadendorf, Lisa A Simms, Kathryn P Burdon, Dale R Nyholt, Karen A Pooley, Nick Orr, Alexander J Stratigos, Anne E Cust, Sarah V Ward, Nicholas K Hayward, Jiali Han, Hans-Joachim Schulze, Alison M Dunning, Julia A Newton Bishop, Florence Demenais, Christopher I Amos, Stuart MacGregor, Mark M Iles |
| Abstract |
Thirteen common susceptibility loci have been reproducibly associated with cutaneous malignant melanoma (CMM). We report the results of an international 2-stage meta-analysis of CMM genome-wide association studies (GWAS). This meta-analysis combines 11 GWAS (5 previously unpublished) and a further three stage 2 data sets, totaling 15,990 CMM cases and 26,409 controls. Five loci not previously associated with CMM risk reached genome-wide significance (P < 5 × 10(-8)), as did 2 previously reported but unreplicated loci and all 13 established loci. Newly associated SNPs fall within putative melanocyte regulatory elements, and bioinformatic and expression quantitative trait locus (eQTL) data highlight candidate genes in the associated regions, including one involved in telomere biology. |
X Demographics
The data shown below were collected from the profiles of 37 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 11 | 30% |
| Australia | 4 | 11% |
| United Kingdom | 3 | 8% |
| Colombia | 1 | 3% |
| Netherlands | 1 | 3% |
| Costa Rica | 1 | 3% |
| Germany | 1 | 3% |
| Canada | 1 | 3% |
| Unknown | 14 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 23 | 62% |
| Scientists | 9 | 24% |
| Practitioners (doctors, other healthcare professionals) | 4 | 11% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 229 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| Italy | 1 | <1% |
| Australia | 1 | <1% |
| Greece | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 224 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 46 | 20% |
| Student > Ph. D. Student | 45 | 20% |
| Student > Bachelor | 25 | 11% |
| Student > Master | 21 | 9% |
| Student > Doctoral Student | 11 | 5% |
| Other | 35 | 15% |
| Unknown | 46 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 56 | 24% |
| Agricultural and Biological Sciences | 49 | 21% |
| Medicine and Dentistry | 40 | 17% |
| Psychology | 4 | 2% |
| Nursing and Health Professions | 3 | 1% |
| Other | 19 | 8% |
| Unknown | 58 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 52. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 June 2016.
All research outputs
#823,518
of 25,837,817 outputs
Outputs from Nature Genetics
#1,499
of 7,639 outputs
Outputs of similar age
#9,912
of 277,410 outputs
Outputs of similar age from Nature Genetics
#24
of 69 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,639 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.7. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 277,410 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.