| Title |
Antidepressants during pregnancy: a French drug utilisation study in EFEMERIS cohort
|
|---|---|
| Published in |
European Archives of Psychiatry and Clinical Neuroscience, May 2018
|
| DOI | 10.1007/s00406-018-0906-2 |
| Pubmed ID | |
| Authors |
Caroline Hurault-Delarue, Isabelle Lacroix, Anne Bénard-Laribière, Jean-Louis Montastruc, Antoine Pariente, Christine Damase-Michel |
| Abstract |
Previous studies have suggested that exposure to some antidepressants (AD) during pregnancy could be associated with an increased risk of congenital malformations and neurodevelopment disorders for the child. We conducted a study to describe the use of AD during pregnancy in France. We performed a drug utilisation study in EFEMERIS, a French cohort of pregnant women. At the time of the present study, 89,170 pregnant women, who were pregnant from 2005 to 2014 in Haute-Garonne were included. Prevalence and incidence of AD prescriptions during pregnancy, characteristics of AD users, and trends in AD use over the 10-year period were studied. During the 10-year study period, 1620 women registered in EFEMERIS (1.8%) received at least one prescription and dispensation for AD during pregnancy: 1363 during the first (1.5%), 591 during the second (0.7%), and 412 during the third (0.5%) trimester. A total of 2874 women (3.2%) got a prescription for an AD during the 3 months before and/or during pregnancy; 2187 of them (76.1%) stopped AD before pregnancy or during the first trimester. Selective serotonin reuptake inhibitors represented the most prescribed class during pregnancy (1.3%). A very slight decrease in the prevalence of AD prescriptions in pregnant women over time (1.7% in 2014 vs 2% in 2005) and some variations within classes were observed. Nearly, 2% of women received antidepressant drugs during pregnancy. This assessment encourages following research on these drugs including the potential risk of neurodevelopmental disorders in children after an exposure to antidepressants during pregnancy. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 50 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 8 | 16% |
| Student > Master | 5 | 10% |
| Student > Postgraduate | 4 | 8% |
| Student > Bachelor | 3 | 6% |
| Other | 3 | 6% |
| Other | 7 | 14% |
| Unknown | 20 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 18% |
| Medicine and Dentistry | 9 | 18% |
| Psychology | 3 | 6% |
| Social Sciences | 2 | 4% |
| Physics and Astronomy | 1 | 2% |
| Other | 3 | 6% |
| Unknown | 23 | 46% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 June 2018.
All research outputs
#19,221,261
of 23,815,455 outputs
Outputs from European Archives of Psychiatry and Clinical Neuroscience
#987
of 1,243 outputs
Outputs of similar age
#258,043
of 332,187 outputs
Outputs of similar age from European Archives of Psychiatry and Clinical Neuroscience
#11
of 15 outputs
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