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From mice to humans: developments in cancer immunoediting

Overview of attention for article published in Journal of Clinical Investigation, August 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

Mentioned by

patent
5 patents

Citations

dimensions_citation
267 Dimensions

Readers on

mendeley
414 Mendeley
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Title
From mice to humans: developments in cancer immunoediting
Published in
Journal of Clinical Investigation, August 2015
DOI 10.1172/jci80004
Pubmed ID
Authors

Michele W.L. Teng, Jerome Galon, Wolf-Herman Fridman, Mark J. Smyth

Abstract

Cancer immunoediting explains the dual role by which the immune system can both suppress and/or promote tumor growth. Although cancer immunoediting was first demonstrated using mouse models of cancer, strong evidence that it occurs in human cancers is now accumulating. In particular, the importance of CD8+ T cells in cancer immunoediting has been shown, and more broadly in those tumors with an adaptive immune resistance phenotype. This Review describes the characteristics of the adaptive immune resistance tumor microenvironment and discusses data obtained in mouse and human settings. The role of other immune cells and factors influencing the effector function of tumor-specific CD8+ T cells is covered. We also discuss the temporal occurrence of cancer immunoediting in metastases and whether it differs from immunoediting in the primary tumor of origin.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 414 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 <1%
India 1 <1%
United Kingdom 1 <1%
Belgium 1 <1%
Denmark 1 <1%
Unknown 409 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 66 16%
Student > Ph. D. Student 65 16%
Researcher 55 13%
Student > Bachelor 46 11%
Student > Doctoral Student 25 6%
Other 53 13%
Unknown 104 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 80 19%
Immunology and Microbiology 61 15%
Medicine and Dentistry 59 14%
Agricultural and Biological Sciences 52 13%
Pharmacology, Toxicology and Pharmaceutical Science 19 5%
Other 28 7%
Unknown 115 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 May 2023.
All research outputs
#3,798,611
of 25,373,627 outputs
Outputs from Journal of Clinical Investigation
#4,735
of 17,180 outputs
Outputs of similar age
#46,919
of 275,994 outputs
Outputs of similar age from Journal of Clinical Investigation
#49
of 105 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 17,180 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.7. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 275,994 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 105 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.