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Genetic Epidemiology

Overview of attention for book
Attention for Chapter: Translating Human Genetics into Novel Drug Targets
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Chapter title
Translating Human Genetics into Novel Drug Targets
Book title
Genetic Epidemiology
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-7868-7_16
Pubmed ID
Book ISBNs
978-1-4939-7867-0, 978-1-4939-7868-7
Authors

Karol Estrada

Abstract

The most important promise of the human genome sequencing project is the identification of the genetic cause of devastating human diseases and the subsequent deliver of novel drug therapies to treat these diseases with high unmet medical need. In the last 10 years we have successfully identified hundreds of genetic loci associated with many traits and diseases. The translation of these findings into novel therapies is not straightforward and poses challenges that are usually overlooked in traditional gene mapping. This chapter describes some of the most common challenges and opportunities to use human genetics to identify and validate novel drug targets.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 2 25%
Other 1 13%
Researcher 1 13%
Unknown 4 50%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 1 13%
Nursing and Health Professions 1 13%
Chemistry 1 13%
Neuroscience 1 13%
Unknown 4 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 June 2018.
All research outputs
#17,413,658
of 25,547,904 outputs
Outputs from Methods in molecular biology
#6,085
of 14,290 outputs
Outputs of similar age
#284,840
of 450,638 outputs
Outputs of similar age from Methods in molecular biology
#591
of 1,485 outputs
Altmetric has tracked 25,547,904 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 14,290 research outputs from this source. They receive a mean Attention Score of 3.5. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 450,638 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,485 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.