Title |
Incidence and risk factors for rectovaginal fistula after low anterior resection for rectal cancer
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Published in |
International Journal of Colorectal Disease, August 2015
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DOI | 10.1007/s00384-015-2340-5 |
Pubmed ID | |
Authors |
Jun Watanabe, Mitsuyoshi Ota, Daisuke Kawaguchi, Hidetaka Shima, Shuhei Kaida, Shunichi Osada, Nobuyuki Kamimukai, Noriyuki Kamiya, Atsushi Ishibe, Kazuteru Watanabe, Ryusei Matsuyama, Hirotoshi Akiyama, Yasushi Ichikawa, Mari Oba, Itaru Endo |
Abstract |
The rectovaginal fistula (RVF) is a rare complication after low anterior resection (LAR) for rectal cancer. The aim of this study was to evaluate the risk factors for RVF after LAR for rectal cancer. This was a retrospective multi-institution study of 371 female rectal cancer patients who underwent LAR with anastomosis between January 2007 and December 2011. Patient-, tumor-, and surgery-related variables were examined by univariate and multivariate analyses. The overall RVF rate was 3.0 % (11/371). The RVF was diagnosed on median postoperative day 83 (15-766). In 81.8 % (9/11) of the patients, the diagnosis of RVF was made after hospital discharge. Multivariate analysis identified prognostic nutritional index (PNI; odds ratio (OR) 6.97; 95 % confidence interval (CI) 1.47-33.08; P = 0.015), preoperative chemotherapy (OR 27.31; CI 3.49-213.62; P = 0.002), tumor size (OR 5.90; CI 1.04-33.47; P = 0.045), intraoperative bleeding (OR 13.91; CI 1.34-144.42; P = 0.027), and lateral lymph node dissection (OR 4.92; CI 1.02-23.63; P = 0.045) as independent risk factors for RVF after LAR. Risk factors of RVF were PNI (<45), preoperative chemotherapy, tumor size (≧50 mm), intraoperative bleeding (≧200 ml), and lateral lymph node dissection. Before an operation, obtaining the information about these risk factors is of great importance in LAR for rectal cancer. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Science communicators (journalists, bloggers, editors) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Japan | 1 | 3% |
Unknown | 38 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 8 | 21% |
Researcher | 4 | 10% |
Student > Master | 3 | 8% |
Student > Doctoral Student | 3 | 8% |
Student > Ph. D. Student | 2 | 5% |
Other | 8 | 21% |
Unknown | 11 | 28% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 23 | 59% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Environmental Science | 1 | 3% |
Computer Science | 1 | 3% |
Chemistry | 1 | 3% |
Other | 0 | 0% |
Unknown | 12 | 31% |