Title |
Interdependence between iron acquisition and biofilm formation in Pseudomonas aeruginosa
|
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Published in |
Journal of Microbiology, June 2018
|
DOI | 10.1007/s12275-018-8114-3 |
Pubmed ID | |
Authors |
Donghoon Kang, Natalia V. Kirienko |
Abstract |
Bacterial biofilms remain a persistent threat to human healthcare due to their role in the development of antimicrobial resistance. To combat multi-drug resistant pathogens, it is crucial to enhance our understanding of not only the regulation of biofilm formation, but also its contribution to bacterial virulence. Iron acquisition lies at the crux of these two subjects. In this review, we discuss the role of iron acquisition in biofilm formation and how hosts impede this mechanism to defend against pathogens. We also discuss recent findings that suggest that biofilm formation can also have the reciprocal effect, influencing siderophore production and iron sequestration. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 20% |
United States | 2 | 13% |
Netherlands | 1 | 7% |
Unknown | 9 | 60% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 13 | 87% |
Scientists | 1 | 7% |
Practitioners (doctors, other healthcare professionals) | 1 | 7% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 159 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 32 | 20% |
Researcher | 26 | 16% |
Student > Master | 20 | 13% |
Student > Bachelor | 17 | 11% |
Other | 5 | 3% |
Other | 14 | 9% |
Unknown | 45 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Immunology and Microbiology | 33 | 21% |
Biochemistry, Genetics and Molecular Biology | 22 | 14% |
Agricultural and Biological Sciences | 16 | 10% |
Medicine and Dentistry | 15 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 7 | 4% |
Other | 17 | 11% |
Unknown | 49 | 31% |