Title |
“It Was Not My Aim to Sleep There”: The Impact of Timing and Location of Sex on Adherence to Coitally-Dependent HIV Pre-exposure Prophylaxis
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Published in |
AIDS and Behavior, June 2018
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DOI | 10.1007/s10461-018-2195-1 |
Pubmed ID | |
Authors |
Fiona Scorgie, Jonathan Stadler, Deborah Baron, Susan Ju, Tshepiso Ikaneng, Zonke Mabude, Sylvia Makgopa, Matshidiso A. Malefo, Kgahlisho N. Manenzhe, Thulani Mazibuko, Hilda Ntjana, Busi Nkala, Thesla Palanee-Phillips, Glenda Gray, Helen Rees, Sinead Delany-Moretlwe |
Abstract |
The FACTS 001 trial found that vaginal pre- and post-coital application of 1% tenofovir gel did not prevent HIV-1 infection amongst young South African women. The trial included a multi-faceted approach to adherence support and collected objective and self-reported adherence measures. Using qualitative data collected from a random sub-set of FACTS 001 participants (135 in-depth interviews at product discontinuation and 13 focus group discussions at dissemination of trial results), we explore the importance of 'place' and 'timing' in shaping acts of sexual intimacy and product adherence. Demographically, this qualitative sub-sample is similar to the trial cohort of predominantly young, unemployed women living with parents or other family members. Sexual intimacy was largely unpredictable and happened across multiple locations in which women had limited privacy, autonomy, or control over the timing of sex. This made adherence to the dosing strategy challenging. Findings may inform the development of future event-driven pre-exposure prophylaxis regimens or products. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | 67% |
United States | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 82 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 12 | 15% |
Student > Ph. D. Student | 11 | 13% |
Researcher | 9 | 11% |
Student > Bachelor | 9 | 11% |
Student > Postgraduate | 3 | 4% |
Other | 9 | 11% |
Unknown | 29 | 35% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 13 | 16% |
Psychology | 8 | 10% |
Nursing and Health Professions | 8 | 10% |
Social Sciences | 5 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
Other | 10 | 12% |
Unknown | 34 | 41% |