| Title |
Structural and histological differences between connective tissue grafts harvested from the lateral palatal mucosa or from the tuberosity area
|
|---|---|
| Published in |
Clinical Oral Investigations, June 2018
|
| DOI | 10.1007/s00784-018-2516-9 |
| Pubmed ID | |
| Authors |
I. Sanz-Martín, E. Rojo, E. Maldonado, G. Stroppa, J. Nart, M. Sanz |
| Abstract |
Tuberosity grafts had a greater percentage of lamina propria and lower percentage of submucosa when compared to lateral palate grafts. The study aims to understand the differences in the structural composition of soft tissue autografts harvested from the lateral palate or the tuberosity. Patients were randomly allocated to receive autografts harvested either from palatal or tuberosity sites to augment horizontal volume deficiencies around single-tooth implants. Tissue biopsies were analyzed for histological and histo-morphometric analysis. Picro-sirius red stain was used to evaluate collagen 1 and 3. Also, immuno-histochemical analysis was performed against MMP1, MMP2, cytokeratin-10, cytokeratin-13, and lysine hydroxylase-2. Twenty specimens were harvested from 9 subjects in the lateral palate group (PG) and 11 subjects in the tuberosity group (TG). The percentage of lamina propria represented 51.08% in the PG group and 72.79% in the TG group, while the area of submucosa was minimal in the TG group representing 4.89% of the total sample vs 25.75% in the PG. The total area of COL-1 and 3 in the TG was 1.19 ± 0.57 and 0.72 ± 0.44 mm2, respectively, while in the PG, the corresponding values were 1.4 ± 0.7 and 1.04 ± 0.5 mm2. The immuno-histochemical analysis generally showed a higher expression of LLH-2, MMP2, CYT-10, and CYT-13 in the TG when compared with the PG. Tuberosity grafts had a greater percentage of lamina propria and lower percentage of submucosa. The collagen content in the lamina propria was similar for both groups while the immuno-histochemical profile showed differences in the antibody expression of the epithelial cells. Tuberosity grafts had more lamina propria and less submocusa, which may be beneficial for volume augmentation. |
X Demographics
The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | 22% |
| Côte d'Ivoire | 1 | 11% |
| Switzerland | 1 | 11% |
| Unknown | 5 | 56% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 78% |
| Scientists | 1 | 11% |
| Practitioners (doctors, other healthcare professionals) | 1 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 128 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 128 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Unspecified | 19 | 15% |
| Student > Master | 14 | 11% |
| Student > Postgraduate | 13 | 10% |
| Professor | 7 | 5% |
| Student > Bachelor | 7 | 5% |
| Other | 20 | 16% |
| Unknown | 48 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 50 | 39% |
| Unspecified | 19 | 15% |
| Biochemistry, Genetics and Molecular Biology | 2 | 2% |
| Nursing and Health Professions | 1 | <1% |
| Agricultural and Biological Sciences | 1 | <1% |
| Other | 5 | 4% |
| Unknown | 50 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2018.
All research outputs
#5,273,297
of 25,543,275 outputs
Outputs from Clinical Oral Investigations
#219
of 1,596 outputs
Outputs of similar age
#93,230
of 342,117 outputs
Outputs of similar age from Clinical Oral Investigations
#5
of 32 outputs
Altmetric has tracked 25,543,275 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,596 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done well, scoring higher than 86% of its peers.
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We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.