Title |
Why the C-statistic is not informative to evaluate early warning scores and what metrics to use
|
---|---|
Published in |
Critical Care, December 2015
|
DOI | 10.1186/s13054-015-0999-1 |
Pubmed ID | |
Authors |
Santiago Romero-Brufau, Jeanne M. Huddleston, Gabriel J. Escobar, Mark Liebow |
Abstract |
Metrics typically used to report the performance of an early warning score (EWS), such as the area under the receiver operator characteristic curve or C-statistic, are not useful for pre-implementation analyses. Because physiological deterioration has an extremely low prevalence of 0.02 per patient-day, these metrics can be misleading. We discuss the statistical reasoning behind this statement and present a novel alternative metric more adequate to operationalize an EWS. We suggest that pre-implementation evaluation of EWSs should include at least two metrics: sensitivity; and either the positive predictive value, number needed to evaluate, or estimated rate of alerts. We also argue the importance of reporting each individual cutoff value. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 4 | 22% |
United States | 2 | 11% |
Puerto Rico | 2 | 11% |
Greece | 1 | 6% |
Canada | 1 | 6% |
Malaysia | 1 | 6% |
France | 1 | 6% |
Unknown | 6 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 7 | 39% |
Members of the public | 5 | 28% |
Science communicators (journalists, bloggers, editors) | 5 | 28% |
Scientists | 1 | 6% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | <1% |
Netherlands | 1 | <1% |
France | 1 | <1% |
Canada | 1 | <1% |
Sri Lanka | 1 | <1% |
Unknown | 122 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 22 | 17% |
Student > Ph. D. Student | 16 | 13% |
Student > Master | 14 | 11% |
Professor | 13 | 10% |
Other | 10 | 8% |
Other | 31 | 24% |
Unknown | 21 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 54 | 43% |
Computer Science | 10 | 8% |
Nursing and Health Professions | 7 | 6% |
Engineering | 7 | 6% |
Mathematics | 7 | 6% |
Other | 17 | 13% |
Unknown | 25 | 20% |