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Adoptive immunotherapy for cancer: building on success

Overview of attention for article published in Nature Reviews Immunology, April 2006
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

Mentioned by

policy
1 policy source
twitter
1 X user
patent
118 patents
facebook
1 Facebook page
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
737 Dimensions

Readers on

mendeley
578 Mendeley
citeulike
3 CiteULike
connotea
5 Connotea
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Title
Adoptive immunotherapy for cancer: building on success
Published in
Nature Reviews Immunology, April 2006
DOI 10.1038/nri1842
Pubmed ID
Authors

Luca Gattinoni, Daniel J. Powell, Steven A. Rosenberg, Nicholas P. Restifo

Abstract

Adoptive cell transfer after host preconditioning by lymphodepletion represents an important advance in cancer immunotherapy. Here, we describe how a lymphopaenic environment enables tumour-reactive T cells to destroy large burdens of metastatic tumour and how the state of differentiation of the adoptively transferred T cells can affect the outcome of treatment. We also discuss how the translation of these new findings might further improve the efficacy of adoptive cell transfer through the use of vaccines, haematopoietic-stem-cell transplantation, modified preconditioning regimens, and alternative methods for the generation and selection of the T cells to be transferred.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 578 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 10 2%
Germany 4 <1%
Canada 2 <1%
Italy 1 <1%
Brazil 1 <1%
Sweden 1 <1%
Switzerland 1 <1%
United Kingdom 1 <1%
France 1 <1%
Other 2 <1%
Unknown 554 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 130 22%
Researcher 117 20%
Student > Master 85 15%
Student > Bachelor 50 9%
Professor > Associate Professor 32 6%
Other 104 18%
Unknown 60 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 179 31%
Medicine and Dentistry 109 19%
Biochemistry, Genetics and Molecular Biology 74 13%
Immunology and Microbiology 74 13%
Chemistry 22 4%
Other 47 8%
Unknown 73 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 April 2024.
All research outputs
#1,547,671
of 24,224,854 outputs
Outputs from Nature Reviews Immunology
#657
of 2,583 outputs
Outputs of similar age
#2,493
of 68,275 outputs
Outputs of similar age from Nature Reviews Immunology
#2
of 19 outputs
Altmetric has tracked 24,224,854 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,583 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 41.9. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 68,275 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.