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Baseline Susceptibility to Pyrethroid and Organophosphate Insecticides in Two Old World Sand Fly Species (Diptera: Psychodidae).

Overview of attention for article published in Medical journal, January 2015
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Title
Baseline Susceptibility to Pyrethroid and Organophosphate Insecticides in Two Old World Sand Fly Species (Diptera: Psychodidae).
Published in
Medical journal, January 2015
Pubmed ID
Authors

Andrew Y Li, Adalberto A Perez de Leon, Kenneth J Linthicum, Seth C Britch, Joshua D Bast, Mustapha Debboun

Abstract

Phlebotomine sand flies are blood-feeding insects that transmit Leishmania parasites that cause various forms of cutaneous and visceral leishmaniasis and sand fly fever viruses (Phlebovirus; Bunyaviridae) in humans. Sand flies pose a significant threat to US military personnel deployed to Leishmania-endemic and sand fly fever endemic regions which include Europe, the Mediterranean basin, Middle East, Central Asia, Southwest Asia, and Africa. A research project supported by the Department of Defense Deployed Warfighter Protection Program was initiated to evaluate the susceptibility of 2 Old World sand fly species, Phlebotomus papatasi and P duboscqi, to a number of commonly used pyrethroid and organophosphate insecticides. A new glass vial bioassay technique based on the CDC bottle assay was developed for this study. The exposure time-mortality relationship at a given insecticide concentration was determined for each insecticide, and their relative toxicity against the 2 sand fly species was ranked based on bioassay results. This study validated the new bioassay technique and also generated baseline insecticide susceptibility data to inform future insecticide resistance monitoring work.

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Geographical breakdown

Country Count As %
Sri Lanka 1 4%
Unknown 22 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 17%
Student > Master 4 17%
Researcher 2 9%
Student > Bachelor 2 9%
Unknown 11 48%
Readers by discipline Count As %
Environmental Science 3 13%
Agricultural and Biological Sciences 3 13%
Medicine and Dentistry 2 9%
Immunology and Microbiology 2 9%
Biochemistry, Genetics and Molecular Biology 1 4%
Other 0 0%
Unknown 12 52%