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Body composition of children with cancer during treatment and in survivorship 1

Overview of attention for article published in American Journal of Clinical Nutrition, August 2015
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Title
Body composition of children with cancer during treatment and in survivorship 1
Published in
American Journal of Clinical Nutrition, August 2015
DOI 10.3945/ajcn.114.099697
Pubmed ID
Authors

Alexia J Murphy, Melinda White, Sarah A Elliott, Liane Lockwood, Andrew Hallahan, Peter Sw Davies

Abstract

Malnutrition as assessed with the use of body-composition measurements is a poorly understood short- and long-term complication of childhood cancer. We aimed to evaluate the body composition of 2 childhood cancer cohorts as follows: 1) children currently undergoing cancer treatment and 2) childhood cancer survivors. We also aimed to compare the prevalence of obesity and undernutrition between the cancer groups and investigate the impact of cancer type on body composition. Eighty-two children during the treatment of cancer and 53 childhood cancer survivors were involved in the study. Height, weight, body cell mass, percentage of fat, fat mass index, and fat-free mass index were assessed. Subjects were compared with age- and sex-matched healthy controls. The on-treatment group had a higher percentage of fat (P = 0.0001) and fat mass index (P = 0.0001) and a significantly lower body cell mass index (P = 0.0001) and fat-free mass index (P = 0.003) than those of matched controls. The survivor group had a significantly higher percentage of fat (P = 0.03) and fat mass index (P = 0.04) and significantly lower body cell mass index (P = 0.0001) than did matched controls. The prevalence of undernutrition was high in both groups with 48% (95% CI: 36%, 60%) of the on-treatment group and 53% (95% CI: 40%, 66%) of the survivors considered undernourished. According to the percentage of fat cutoffs, significantly more on-treatment patients were obese (55%; 95% CI: 40%, 60%) than were survivors (26%; 95% CI: 14%, 38%) (P = 0.005). There were no statistically significant differences in body composition between cancer types in either the on-treatment or the survivor group. Overnutrition and undernutrition are major concerns in the short and long term for children with cancer. Children treated for cancer have increased fat mass and decreased body cell mass, which are evident during treatment and in survivorship. This trial was registered at http://www.ANZCTR.org.au as ACTRN12614001279617 and ACTRN12614001269628.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 124 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 124 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 16%
Student > Master 19 15%
Student > Bachelor 12 10%
Student > Ph. D. Student 12 10%
Student > Postgraduate 7 6%
Other 15 12%
Unknown 39 31%
Readers by discipline Count As %
Medicine and Dentistry 39 31%
Nursing and Health Professions 18 15%
Unspecified 5 4%
Agricultural and Biological Sciences 4 3%
Psychology 3 2%
Other 11 9%
Unknown 44 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 September 2016.
All research outputs
#6,354,664
of 25,374,917 outputs
Outputs from American Journal of Clinical Nutrition
#6,733
of 12,611 outputs
Outputs of similar age
#67,728
of 276,264 outputs
Outputs of similar age from American Journal of Clinical Nutrition
#61
of 96 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 12,611 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 38.2. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,264 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 96 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.