Title |
AIGO: Towards a unified framework for the Analysis and the Inter-comparison of GO functional annotations
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Published in |
BMC Bioinformatics, November 2011
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DOI | 10.1186/1471-2105-12-431 |
Pubmed ID | |
Authors |
Michael Defoin-Platel, Matthew M Hindle, Artem Lysenko, Stephen J Powers, Dimah Z Habash, Christopher J Rawlings, Mansoor Saqi |
Abstract |
In response to the rapid growth of available genome sequences, efforts have been made to develop automatic inference methods to functionally characterize them. Pipelines that infer functional annotation are now routinely used to produce new annotations at a genome scale and for a broad variety of species. These pipelines differ widely in their inference algorithms, confidence thresholds and data sources for reasoning. This heterogeneity makes a comparison of the relative merits of each approach extremely complex. The evaluation of the quality of the resultant annotations is also challenging given there is often no existing gold-standard against which to evaluate precision and recall. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 3 | 7% |
France | 1 | 2% |
Brazil | 1 | 2% |
Malaysia | 1 | 2% |
South Africa | 1 | 2% |
Belgium | 1 | 2% |
Japan | 1 | 2% |
United States | 1 | 2% |
Unknown | 34 | 77% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 15 | 34% |
Student > Ph. D. Student | 11 | 25% |
Other | 3 | 7% |
Student > Master | 3 | 7% |
Student > Postgraduate | 3 | 7% |
Other | 4 | 9% |
Unknown | 5 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 27 | 61% |
Computer Science | 6 | 14% |
Biochemistry, Genetics and Molecular Biology | 4 | 9% |
Mathematics | 2 | 5% |
Unknown | 5 | 11% |