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CXCL16 in Vascular Pathology Research: from Macro Effects to microRNAs

Overview of attention for article published in Journal of atherosclerosis and thrombosis, August 2015
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  • Above-average Attention Score compared to outputs of the same age and source (58th percentile)

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Title
CXCL16 in Vascular Pathology Research: from Macro Effects to microRNAs
Published in
Journal of atherosclerosis and thrombosis, August 2015
DOI 10.5551/jat.29942
Pubmed ID
Authors

Ivan Jovanović, Maja Zivković, Tamara Djurić, Milan Popović, Dragan Alavantić, Aleksandra Stanković

Abstract

Chemokines and their receptors have become significant factors in atherosclerosis research. CXCL16 is a multifunctional agent located on a separate locus to all other known chemokines and binds only to its "unique" receptor named CXCR6. As a scavenger receptor, adhesion molecule, and chemokine, it quickly became an interesting target in atherosclerosis research as all its functions have a role in vascular pathology. The investigation of the role of CXCL16 in atherosclerosis, although shown in in vitro studies, animal knockout models, and CXCL16 gene polymorphisms, haplotypes, and circulating levels, still shows puzzling results. Genetic and epigenetic studies have just scratched the surface of research necessary for a better assessment of the significance and perspective of this marker in plaque development and progression. In this review, we will summarize current knowledge about CXCL16 in atherosclerosis. Additionally, we will point out the importance of bioinformatics tools for the detection of potentially new CXCL16 regulatory networks through microRNA activity. This review aims to provide a better understanding of the underlying mechanisms, define more specific biomarkers, and discover new therapeutic targets.

X Demographics

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The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 25%
Student > Bachelor 4 20%
Student > Ph. D. Student 3 15%
Professor 1 5%
Student > Master 1 5%
Other 1 5%
Unknown 5 25%
Readers by discipline Count As %
Immunology and Microbiology 3 15%
Biochemistry, Genetics and Molecular Biology 2 10%
Agricultural and Biological Sciences 2 10%
Medicine and Dentistry 2 10%
Computer Science 1 5%
Other 3 15%
Unknown 7 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2015.
All research outputs
#16,721,208
of 25,373,627 outputs
Outputs from Journal of atherosclerosis and thrombosis
#384
of 708 outputs
Outputs of similar age
#157,303
of 277,643 outputs
Outputs of similar age from Journal of atherosclerosis and thrombosis
#5
of 17 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 708 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 277,643 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.