Title |
Molecular characterization of an imported dengue virus serotype 4 isolate from Thailand
|
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Published in |
Archives of Virology, June 2018
|
DOI | 10.1007/s00705-018-3906-7 |
Pubmed ID | |
Authors |
Ling Mo, Jiandong Shi, Xiaofang Guo, Zhaoping Zeng, Ningzhu Hu, Jing Sun, Meini Wu, Hongning Zhou, Yunzhang Hu |
Abstract |
The epidemic of dengue virus infections has spread markedly in Yunnan province of China in recent years due to an increase in the number of imported dengue cases. To the best of our knowledge, the present study is the first to report a whole genome sequence and molecular characterization of an imported DENV-4 isolate from Thailand. The current strain, 2013JH285, has an RNA genome of 10,772 nucleotides that shares 99.0% nucleotide and 99.7% amino acid sequence identity with the 2013 Thailand strain CTI2-13. Phylogenetic analysis of the whole genome sequence revealed that the 2013JH285 strain belongs to genotype I of DENV-4. Recombination analysis suggested that the 2013JH285 strain originated from inter-genotypic recombination of DENV-4 strains. The new complete DENV-4 genome sequence reported here might contribute to further understanding of the molecular epidemiology and disease surveillance of DENV-4 in China. |
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Unknown | 1 | 100% |
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Members of the public | 1 | 100% |
Mendeley readers
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Unknown | 16 | 100% |
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Researcher | 3 | 19% |
Student > Doctoral Student | 2 | 13% |
Librarian | 1 | 6% |
Student > Ph. D. Student | 1 | 6% |
Student > Bachelor | 1 | 6% |
Other | 2 | 13% |
Unknown | 6 | 38% |
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Biochemistry, Genetics and Molecular Biology | 3 | 19% |
Medicine and Dentistry | 3 | 19% |
Immunology and Microbiology | 2 | 13% |
Agricultural and Biological Sciences | 2 | 13% |
Unknown | 6 | 38% |