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PET/CT versus conventional CT for detection of lymph node metastases in patients with locally advanced bladder cancer

Overview of attention for article published in BMC Urology, August 2015
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Title
PET/CT versus conventional CT for detection of lymph node metastases in patients with locally advanced bladder cancer
Published in
BMC Urology, August 2015
DOI 10.1186/s12894-015-0080-z
Pubmed ID
Authors

Firas Aljabery, Gunnar Lindblom, Susann Skoog, Ivan Shabo, Hans Olsson, Johan Rosell, Staffan Jahnson

Abstract

We studied patients treated with radical cystectomy for locally advanced bladder cancer to compare the results of both preoperative positron emission tomography/computed tomography (PET/CT) and conventional CT with the findings of postoperative histopathological evaluation of lymph nodes. Patients who had bladder cancer and were candidates for cystectomy underwent preoperative PET/CT using 18-fluorodeoxyglucose (FDG) and conventional CT. The results regarding lymph node involvement were independently evaluated by two experienced radiologists and were subsequently compared with histopathology results, the latter of which were reassessed by an experienced uropathologist (HO). There were 54 evaluable patients (mean age 68 years, 47 [85 %] males and 7 [15 %] females) with pT and pN status as follows: < pT2-14 (26 %), pT2-10 (18 %), and > pT2-30 (56 %); pN0 37 (69 %) and pN+ 17 (31 %). PET/CT showed positive lymph nodes in 12 patients (22 %), and 7 of those cases were confirmed by histopathology; the corresponding results for conventional CT were 11 (20 %) and 7 patients (13 %), respectively. PET/CT had 41 % sensitivity, 86 % specificity, 58 % PPV, and 76 % NPV, whereas the corresponding figures for conventional CT were 41 %, 89 %, 64 %, and 77 %. Additional analyses of the right and left side of the body or in specified anatomical regions gave similar results. In this study, PET/CT and conventional CT had similar low sensitivity in detecting and localizing regional lymph node metastasis in bladder cancer.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Tunisia 1 3%
Unknown 33 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 21%
Student > Bachelor 4 12%
Student > Ph. D. Student 4 12%
Student > Doctoral Student 2 6%
Lecturer 2 6%
Other 6 18%
Unknown 9 26%
Readers by discipline Count As %
Medicine and Dentistry 22 65%
Social Sciences 1 3%
Biochemistry, Genetics and Molecular Biology 1 3%
Unknown 10 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 April 2016.
All research outputs
#18,423,683
of 22,824,164 outputs
Outputs from BMC Urology
#522
of 751 outputs
Outputs of similar age
#191,960
of 266,184 outputs
Outputs of similar age from BMC Urology
#11
of 14 outputs
Altmetric has tracked 22,824,164 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 751 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
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We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.