| Title |
Marijuana Use in Epilepsy: The Myth and the Reality
|
|---|---|
| Published in |
Current Neurology and Neuroscience Reports, August 2015
|
| DOI | 10.1007/s11910-015-0586-5 |
| Pubmed ID | |
| Authors |
Kamil Detyniecki, Lawrence Hirsch |
| Abstract |
Marijuana has been utilized as a medicinal plant to treat a variety of conditions for nearly five millennia. Over the past few years, there has been an unprecedented interest in using cannabis extracts to treat epilepsy, spurred on by a few refractory pediatric cases featured in the media that had an almost miraculous response to cannabidiol-enriched marijuana extracts. This review attempts to answer the most important questions a clinician may have regarding the use of marijuana in epilepsy. First, we review the preclinical and human evidences for the anticonvulsant properties of the different cannabinoids, mainly tetrahydrocannabinol (THC) and cannabidiol (CBD). Then, we explore the safety data from animal and human studies. Lastly, we attempt to reconcile the controversy regarding physicians' and patients' opinions about whether the available evidence is sufficient to recommend the use of marijuana to treat epilepsy. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 33% |
| Unknown | 4 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 83% |
| Practitioners (doctors, other healthcare professionals) | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 165 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| Brazil | 1 | <1% |
| Unknown | 162 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 27 | 16% |
| Student > Ph. D. Student | 19 | 12% |
| Researcher | 19 | 12% |
| Student > Master | 19 | 12% |
| Other | 14 | 8% |
| Other | 30 | 18% |
| Unknown | 37 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 30 | 18% |
| Pharmacology, Toxicology and Pharmaceutical Science | 18 | 11% |
| Agricultural and Biological Sciences | 16 | 10% |
| Psychology | 12 | 7% |
| Neuroscience | 9 | 5% |
| Other | 36 | 22% |
| Unknown | 44 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 May 2016.
All research outputs
#4,079,119
of 23,577,654 outputs
Outputs from Current Neurology and Neuroscience Reports
#228
of 938 outputs
Outputs of similar age
#51,173
of 268,874 outputs
Outputs of similar age from Current Neurology and Neuroscience Reports
#6
of 14 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 938 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,874 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.