| Title |
Seasonal variation in acute gouty arthritis: data from Nationwide Inpatient Sample
|
|---|---|
| Published in |
Clinical Rheumatology, August 2015
|
| DOI | 10.1007/s10067-015-3042-7 |
| Pubmed ID | |
| Authors |
Paras Karmacharya, Ranjan Pathak, Madan Raj Aryal, Smith Giri, Anthony A. Donato |
| Abstract |
Studies describing seasonal variations in acute gouty arthritis note seasonal variation, but disagree on timing, with most showing a peak in spring months while others show peaks later in the year. Various theories on the effect of weather and immune system changes on the chronobiology of monosodium urate crystals' equilibrium and precipitation have been proposed. We aimed to shed light on this question by examining the seasonal variation in the incidence of acute gouty arthritis in the USA using a large inpatient database. We used the Nationwide Inpatient Sample (NIS) database to identify patients aged ≥18 years with primarydiagnosis of acute gouty arthritis (International Classification of Diseases, 9th Revision, Clinical Modificationcode 274.01) from 2009-2011 during hospitalization. We used the Edwards recognition and estimation ofcyclic trend method to study the seasonal variation of the incidence of acute gout and z-test to compare theseasonal incidences. A total of 28,172 hospitalizations with primary diagnosis of acute gouty arthritis were reported in the USA from 2009-2011. The peak incidence of acute gout was seen in November (peak/low ratio 1.34, 95 % CI 1.29-1.38, p < 0.05). The highest number of hospitalizations was observed in autumn months while the lowest incidence was observed in spring (28.12 vs. 23.13 %, p < 0.001). The peak incidence of acute gout seems to be in the fall with its peak in the month of November. This seasonality may shed light into the pathophysiology of acute attacks and better management of patients with gout who are at risk of acute attacks. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 40% |
| Iraq | 1 | 20% |
| Switzerland | 1 | 20% |
| United States | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Scientists | 1 | 20% |
| Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 23 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 6 | 26% |
| Student > Doctoral Student | 3 | 13% |
| Student > Ph. D. Student | 3 | 13% |
| Student > Postgraduate | 2 | 9% |
| Other | 1 | 4% |
| Other | 2 | 9% |
| Unknown | 6 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 5 | 22% |
| Nursing and Health Professions | 4 | 17% |
| Agricultural and Biological Sciences | 2 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
| Social Sciences | 1 | 4% |
| Other | 1 | 4% |
| Unknown | 9 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 August 2015.
All research outputs
#12,873,978
of 22,824,164 outputs
Outputs from Clinical Rheumatology
#1,542
of 3,001 outputs
Outputs of similar age
#116,031
of 264,591 outputs
Outputs of similar age from Clinical Rheumatology
#29
of 49 outputs
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