| Title |
Translocation of polyampholytes and intrinsically disordered proteins⋆
|
|---|---|
| Published in |
The European Physical Journal E, June 2018
|
| DOI | 10.1140/epje/i2018-11686-7 |
| Pubmed ID | |
| Authors |
A. Johner, J. F. Joanny |
| Abstract |
Polyampholytes are polymers carrying electrical charges of both signs along their backbone. We consider synthetic polyampholytes with a quenched random charge sequence and intrinsically disordered proteins, which have a well-defined charge sequence and behave like polyampholytes in the denaturated state. We study their translocation driven by an electric field through a pore. The role of disorder along the charge sequence of synthetic polyampholytes is analyzed. We show how disorder slows down the translocation dynamics. For intrinsically disordered proteins, the translocation vs. rejection rates by the pore depends on which end is engaged in the translocation channel. We discuss the rejection time, the blockade time distributions and the translocation speed for the charge sequence of two specific intrinsically disordered proteins differing in length and structure. |
Mendeley readers
The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 11 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 4 | 36% |
| Professor | 2 | 18% |
| Other | 1 | 9% |
| Professor > Associate Professor | 1 | 9% |
| Student > Postgraduate | 1 | 9% |
| Other | 0 | 0% |
| Unknown | 2 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemical Engineering | 2 | 18% |
| Biochemistry, Genetics and Molecular Biology | 2 | 18% |
| Physics and Astronomy | 2 | 18% |
| Nursing and Health Professions | 1 | 9% |
| Chemistry | 1 | 9% |
| Other | 1 | 9% |
| Unknown | 2 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 July 2018.
All research outputs
#1,488,221
of 23,498,099 outputs
Outputs from The European Physical Journal E
#85
of 650 outputs
Outputs of similar age
#33,454
of 329,086 outputs
Outputs of similar age from The European Physical Journal E
#5
of 17 outputs
Altmetric has tracked 23,498,099 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 650 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,086 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.