| Title |
Urinary pyridinoline cross-links as biomarkers of osteogenesis imperfecta
|
|---|---|
| Published in |
Orphanet Journal of Rare Diseases, August 2015
|
| DOI | 10.1186/s13023-015-0315-9 |
| Pubmed ID | |
| Authors |
Uschi Lindert, Marius Kraenzlin, Ana Belinda Campos-Xavier, Matthias R. Baumgartner, Luisa Bonafé, Cecilia Giunta, Marianne Rohrbach |
| Abstract |
Osteogenesis imperfecta (OI) is a group of genetic heterogeneous connective tissue disorders characterized by increased bone fragility and susceptibility to fractures. Laboratory diagnosis relies on time-consuming and cost-intensive biochemical and molecular genetics analyses. Therefore, it is desirable to identify and establish new diagnostic markers for OI that are reliable, cost-effective and easily accessible. In our study we have identified the ratio of the urinary pyridinoline cross-links lysyl-pyridinoline and hydroxylysyl-pyridinoline as a promising, time- and cost-effective biomarker for osteogenesis imperfecta, that could be used furthermore to investigate cases of suspected non-accidental injury in infants. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 67% |
| Members of the public | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 24 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 4 | 17% |
| Student > Ph. D. Student | 3 | 13% |
| Student > Bachelor | 2 | 8% |
| Researcher | 2 | 8% |
| Professor > Associate Professor | 2 | 8% |
| Other | 4 | 17% |
| Unknown | 7 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 4 | 17% |
| Medicine and Dentistry | 3 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 8% |
| Chemistry | 2 | 8% |
| Agricultural and Biological Sciences | 1 | 4% |
| Other | 3 | 13% |
| Unknown | 9 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 August 2021.
All research outputs
#14,235,639
of 22,826,360 outputs
Outputs from Orphanet Journal of Rare Diseases
#1,567
of 2,618 outputs
Outputs of similar age
#138,534
of 267,486 outputs
Outputs of similar age from Orphanet Journal of Rare Diseases
#27
of 40 outputs
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