| Title |
Acute liver failure due to zinc phosphide containing rodenticide poisoning: Clinical features and prognostic indicators of need for liver transplantation
|
|---|---|
| Published in |
Indian Journal of Gastroenterology, August 2015
|
| DOI | 10.1007/s12664-015-0583-2 |
| Pubmed ID | |
| Authors |
Vivek Saraf, Supriya Pande, Unnikrishnan Gopalakrishnan, Dinesh Balakrishnan, Ramachandran N. Menon, O. V. Sudheer, Puneet Dhar, S. Sudhindran |
| Abstract |
Zinc phosphide (ZnP) containing rodenticide poisoning is a recognized cause of acute liver failure (ALF) in India. When standard conservative measures fail, the sole option is liver transplantation. Records of 41 patients admitted to a single centre with ZnP-induced ALF were reviewed to identify prognostic indicators for requirement of liver transplantation. Patients were analyzed in two groups: group I (n = 22) consisted of patients who either underwent a liver transplant (n = 14) or died without a transplant (n = 8); group II (n = 19) comprised those who survived without liver transplantation. International normalized ratio (INR) in group I was 9 compared to 3 in group II (p < 0.001). Encephalopathy occurred only in group I. Model for End-Stage Liver Disease (MELD) score in group I was 41 compared to 24 in group II (p < 0.001). MELD score of 36 (sensitivity of 86.7 %, specificity of 90 %) or a combination of INR of 6 and encephalopathy (sensitivity of 100 %, specificity of 83 %) were the best indicators of mortality. Such patients should undergo urgent liver transplantation. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 3% |
| Unknown | 33 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Postgraduate | 5 | 15% |
| Researcher | 4 | 12% |
| Student > Master | 4 | 12% |
| Other | 4 | 12% |
| Professor | 2 | 6% |
| Other | 9 | 26% |
| Unknown | 6 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 16 | 47% |
| Nursing and Health Professions | 4 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 9% |
| Agricultural and Biological Sciences | 1 | 3% |
| Unspecified | 1 | 3% |
| Other | 2 | 6% |
| Unknown | 7 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 June 2016.
All research outputs
#18,425,370
of 22,826,360 outputs
Outputs from Indian Journal of Gastroenterology
#222
of 343 outputs
Outputs of similar age
#193,531
of 268,158 outputs
Outputs of similar age from Indian Journal of Gastroenterology
#2
of 6 outputs
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So far Altmetric has tracked 343 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
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