Title |
Active surveillance for multidrug-resistant Gram-negative bacteria in the intensive care unit
|
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Published in |
Pathology, October 2015
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DOI | 10.1097/pat.0000000000000302 |
Pubmed ID | |
Authors |
Iain J. Abbott, Adam W.J. Jenney, Denis W. Spelman, David V. Pilcher, Hanna E. Sidjabat, Leisha J. Richardson, David L. Paterson, Anton Y. Peleg |
Abstract |
A short-term program of performing serial active screening cultures (ASC) in the intensive care unit was instituted to establish a method for the detection of antibiotic-resistant Gram-negative bacteria (GNB) and the local rates of colonisation. Of all submitted ASC, 25.9% (30/116 collected swabs) isolated an antibiotic-resistant GNB. ChromID ESBL agar (bioMérieux, France) identified the majority of these organisms, with the additional antibiotic-impregnated media [MacConkey agar (MCA) with ciprofloxacin, MCA with gentamicin and MCA with ceftazidime] adding limited benefit. Compared to swabs performed on admission, 37.8% (14/37) of patients cultured a new antibiotic-resistant isolate on discharge. Serial screening in intensive care has the ability to identify patients with unrecognised colonisation with antibiotic-resistant GNB; however, the increase in the laboratory workload and logistical challenges in the collection of the surveillance swabs may limit this program's expansion. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 29% |
United Kingdom | 2 | 29% |
Spain | 1 | 14% |
Unknown | 2 | 29% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 43% |
Scientists | 2 | 29% |
Science communicators (journalists, bloggers, editors) | 1 | 14% |
Practitioners (doctors, other healthcare professionals) | 1 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Colombia | 1 | 3% |
Unknown | 34 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 6 | 17% |
Student > Master | 5 | 14% |
Researcher | 4 | 11% |
Student > Postgraduate | 3 | 9% |
Student > Doctoral Student | 2 | 6% |
Other | 9 | 26% |
Unknown | 6 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 9 | 26% |
Agricultural and Biological Sciences | 7 | 20% |
Biochemistry, Genetics and Molecular Biology | 6 | 17% |
Nursing and Health Professions | 2 | 6% |
Unspecified | 1 | 3% |
Other | 3 | 9% |
Unknown | 7 | 20% |