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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Pre‐diagnostic circulating insulin‐like growth factor‐I and bladder cancer risk in the European Prospective Investigation into Cancer and Nutrition
|
|---|---|
| Published in |
International Journal of Cancer, September 2018
|
| DOI | 10.1002/ijc.31650 |
| Pubmed ID | |
| Authors |
Crystal Lin, Ruth C. Travis, Paul N. Appleby, Sarah Tipper, Elisabete Weiderpass, Jenny Chang‐Claude, Inger T. Gram, Rudolf Kaaks, Lambertus A. Kiemeney, Börje Ljungberg, Rosario Tumino, Anne Tjønneland, Nina Roswall, Kim Overvad, Marie‐Christine Boutron‐Ruault, Francesca Romana Manciniveri, Gianluca Severi, Antonia Trichopoulou, Giovanna Masala, Carlotta Sacerdote, Claudia Agnoli, Salvatore Panico, Bas Bueno‐de‐Mesquita, Petra H. Peeters, Elena Salamanca‐Fernández, Maria‐Dolores Chirlaque, Eva Ardanaz, Miren Dorronsoro, Virginia Menéndez, Leila Luján‐Barroso, Fredrik Liedberg, Heinz Freisling, Marc Gunter, Dagfinn Aune, Amanda J. Cross, Elio Riboli, Timothy J. Key, Aurora Perez‐Cornago |
| Abstract |
Previous in vitro and case-control studies have found an association between the insulin-like growth factor (IGF)-axis and bladder cancer risk. Circulating concentrations of IGF-I have also been found to be associated with an increased risk of several cancer types; however, the relationship between pre-diagnostic circulating IGF-I concentrations and bladder cancer has never been studied prospectively. We investigated the association of pre-diagnostic plasma concentrations of IGF-I with risk of overall bladder cancer and urothelial cell carcinoma (UCC) in a case-control study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. A total of 843 men and women diagnosed with bladder cancer between 1992 and 2005 were matched with 843 controls by recruitment centre, sex, age at recruitment, date of blood collection, duration of follow-up, time of day and fasting status at blood collection using an incidence density sampling protocol. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using conditional logistic regression with adjustment for smoking status. No association was found between pre-diagnostic circulating IGF-I concentration and overall bladder cancer risk (adjusted OR for highest versus lowest fourth: 0.91, 95% CI: 0.66-1.24, Ptrend =0.40) or UCC (n of cases=776; 0.91, 0.65-1.26, Ptrend =0.40). There was no significant evidence of heterogeneity in the association of IGF-I with bladder cancer risk by tumour aggressiveness, sex, smoking status, or by time between blood collection and diagnosis (Pheterogeneity >0.05 for all). This first prospective study indicates no evidence of an association between plasma IGF-I concentrations and bladder cancer risk. This article is protected by copyright. All rights reserved. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 45 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 8 | 18% |
| Student > Bachelor | 8 | 18% |
| Student > Ph. D. Student | 3 | 7% |
| Professor | 2 | 4% |
| Student > Doctoral Student | 2 | 4% |
| Other | 8 | 18% |
| Unknown | 14 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 15 | 33% |
| Nursing and Health Professions | 5 | 11% |
| Engineering | 2 | 4% |
| Unspecified | 1 | 2% |
| Business, Management and Accounting | 1 | 2% |
| Other | 6 | 13% |
| Unknown | 15 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 November 2018.
All research outputs
#15,012,809
of 23,094,276 outputs
Outputs from International Journal of Cancer
#9,567
of 11,790 outputs
Outputs of similar age
#201,642
of 337,499 outputs
Outputs of similar age from International Journal of Cancer
#65
of 130 outputs
Altmetric has tracked 23,094,276 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,790 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 337,499 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 130 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.