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Progranulin

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Cover of 'Progranulin'

Table of Contents

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    Book Overview
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    Chapter 1 A Brief Overview of Progranulin in Health and Disease
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    Chapter 2 Chromatographic Methods for the Purification of Granulin Peptides
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    Chapter 3 Methods for Expression and Purification of Biologically Active Recombinant Progranulin
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    Chapter 4 Large-Scale Generation of Recombinant Granulin Peptides in E. coli
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    Chapter 5 Nuclear Magnetic Resonance Spectroscopy in Analysis of Granulin Three-Dimensional Structure and Cysteine Bridging
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    Chapter 6 Data Mining: Applying the AD&FTD Mutation Database to Progranulin
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    Chapter 7 Measurement of Circulating Progranulin (PGRN/GP88/GEP) by Enzyme-Linked Immunosorbent Assay and Application in Human Diseases
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    Chapter 8 Immunohistochemical Detection of Progranulin (PGRN/GP88/GEP) in Tumor Tissues as a Cancer Prognostic Biomarker
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    Chapter 9 Analysis of Progranulin-Mediated Akt and MAPK Activation
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    Chapter 10 Mouse Monoclonal Antibodies Against Progranulin (PGRN/GEP) as Therapeutics in Preclinical Cancer Models
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    Chapter 11 Methods to Analyze the Role of Progranulin (PGRN/GEP) on Cancer Stem Cell Features
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    Chapter 12 Methods to Study the Role of Progranulin in the Tumor Microenvironment
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    Chapter 13 Methods to Investigate the Molecular Basis of Progranulin Action on Neurons In Vivo Using Caenorhabditis elegans
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    Chapter 14 The Use of Caenorhabditis elegans to Study Progranulin in the Regulation of Programmed Cell Death and Stress Response
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    Chapter 15 Application of Zebrafish and Knockdown Technology to Define Progranulin Neuronal Function
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    Chapter 16 Methods to Investigate the Molecular Basis of Progranulin Actions on Brain and Behavior In Vivo Using Knockout Mice
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    Chapter 17 Methods to Investigate the Protection Against Neurodegenerative Disorders Provided by Progranulin Gene Transfer in the Brain
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    Chapter 18 The Interaction Between Progranulin with Sortilin and the Lysosome
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    Chapter 19 Methods to Study the Role of Progranulin in Preimplantation Mouse Embryo Development
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    Chapter 20 Establishment of a Modified Collagen-Induced Arthritis Mouse Model to Investigate the Anti-inflammatory Activity of Progranulin in Inflammatory Arthritis
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    Chapter 21 Methods for Studying the Function of Progranulin in Atherosclerosis Using Both Knockout Mice Models and In Vitro Studies
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    Chapter 22 Methods to Investigate the Roles of Progranulin in Angiogenesis Using In Vitro Strategies and Transgenic Mouse Models
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Title
Progranulin
Published by
Springer New York, July 2018
DOI 10.1007/978-1-4939-8559-3
ISBNs
978-1-4939-8557-9, 978-1-4939-8559-3
Editors

Andrew Bateman, Hugh P.J. Bennett, Siu Tim Cheung

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X Demographics

The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 1 3%
Unknown 32 97%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 1 3%
Unknown 32 97%