↓ Skip to main content

Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA

Overview of attention for article published in Nature Methods, November 2009
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (76th percentile)

Mentioned by

twitter
2 X users
patent
3 patents

Citations

dimensions_citation
103 Dimensions

Readers on

mendeley
291 Mendeley
citeulike
13 CiteULike
connotea
2 Connotea
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA
Published in
Nature Methods, November 2009
DOI 10.1038/nmeth.1404
Pubmed ID
Authors

Alon Goren, Fatih Ozsolak, Noam Shoresh, Manching Ku, Mazhar Adli, Chris Hart, Melissa Gymrek, Or Zuk, Aviv Regev, Patrice M Milos, Bradley E Bernstein

Abstract

Chromatin structure and transcription factor localization can be assayed genome-wide by sequencing genomic DNA fractionated by protein occupancy or other properties, but current technologies involve multiple steps that introduce bias and inefficiency. Here we apply a single-molecule approach to directly sequence chromatin immunoprecipitated DNA with minimal sample manipulation. This method is compatible with just 50 pg of DNA and should thus facilitate charting chromatin maps from limited cell populations.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 291 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 19 7%
Italy 3 1%
United Kingdom 3 1%
France 2 <1%
Japan 2 <1%
Korea, Republic of 1 <1%
Portugal 1 <1%
Canada 1 <1%
Argentina 1 <1%
Other 5 2%
Unknown 253 87%

Demographic breakdown

Readers by professional status Count As %
Researcher 97 33%
Student > Ph. D. Student 80 27%
Professor > Associate Professor 26 9%
Professor 24 8%
Student > Master 10 3%
Other 35 12%
Unknown 19 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 195 67%
Biochemistry, Genetics and Molecular Biology 43 15%
Medicine and Dentistry 10 3%
Immunology and Microbiology 5 2%
Engineering 5 2%
Other 14 5%
Unknown 19 7%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 October 2022.
All research outputs
#6,234,274
of 23,575,346 outputs
Outputs from Nature Methods
#3,435
of 5,043 outputs
Outputs of similar age
#40,208
of 168,673 outputs
Outputs of similar age from Nature Methods
#31
of 42 outputs
Altmetric has tracked 23,575,346 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 5,043 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 35.3. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 168,673 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.