| Title |
The level of DNA damage in mouse hematopoietic cells and in frog and human blood cells, as induced by the action of reactive oxygen species in vitro
|
|---|---|
| Published in |
Radiation and Environmental Biophysics, February 2018
|
| DOI | 10.1007/s00411-018-0732-y |
| Pubmed ID | |
| Authors |
Nikolay Sirota, Elena Kuznetsova, Irina Mitroshina |
| Abstract |
Comparative studies of the level of DNA damage induced in vitro by X-rays (0-8 Gy) or hydrogen peroxide (0-300 µM) in cells of blood, spleen, and bone marrow of mice and in blood cells of frogs and humans were performed using the alkaline comet assay. For both agents, the levels of induced DNA damage in leucocytes/splenocytes of mice were higher than those in blood cells of frogs and humans, while in human leucocytes, they were comparable with those in frog blood cells. The rate of DNA repair in frog blood cells was very slow. The results suggest that the levels of radiation-induced DNA damage are not in accordance with species radiosensitivity (according to LD50/30) but rather with the intrinsic peculiarities of cells. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Russia | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 5 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 2 | 40% |
| Student > Ph. D. Student | 1 | 20% |
| Student > Bachelor | 1 | 20% |
| Other | 1 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Environmental Science | 1 | 20% |
| Nursing and Health Professions | 1 | 20% |
| Agricultural and Biological Sciences | 1 | 20% |
| Medicine and Dentistry | 1 | 20% |
| Unknown | 1 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 July 2018.
All research outputs
#19,221,261
of 23,815,455 outputs
Outputs from Radiation and Environmental Biophysics
#374
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Outputs of similar age
#259,682
of 332,821 outputs
Outputs of similar age from Radiation and Environmental Biophysics
#4
of 6 outputs
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