| Title |
Long scan depth optical coherence tomography on imaging accommodation: impact of enhanced axial resolution, signal-to-noise ratio and speed
|
|---|---|
| Published in |
Eye and Vision, July 2018
|
| DOI | 10.1186/s40662-018-0111-4 |
| Pubmed ID | |
| Authors |
Yilei Shao, Aizhu Tao, Hong Jiang, Meixiao Shen, Dexi Zhu, Fan Lu, Carol L. Karp, Yufeng Ye, Jianhua Wang |
| Abstract |
Spectral domain optical coherence tomography (SD-OCT) was a useful tool to study accommodation in human eye, but the maximum image depth is limited due to the decreased signal-to-noise ratio (SNR). In this study, improving optical resolutions, speeds and the SNR were achieved by custom built SD-OCT, and the evaluation of the impact of the improvement during accommodation was investigated. Three systems with different spectrometer designs, including two Charge Coupled Device (CCD) cameras and one Complementary Metal-Oxide-Semiconductor Transistor (CMOS) camera, were tested. We measured the point spread functions of a mirror at different positions to obtain the axial resolution and the SNR of three OCT systems powered with a light source with a 50 nm bandwidth, centered at a wavelength of 840 nm. Two normal subjects, aged 26 and 47, respectively, and one 75-year-old patient with an intraocular lens implanted were imaged. The results indicated that spectrometers using cameras with 4096 camera pixels optimized the axial resolutions, due to the use of the full spectrum provided by the light source. The CCD camera system with 4096 pixels had the highest SNR and the best image quality. The system with the CMOS camera with 4096 pixels had the highest speed but had a compromised SNR compared to the CCD camera with 4096 pixels. Using these three OCT systems, we imaged the anterior segment of the human eye before and after accommodation, which showed similar results among the different systems. The system using the CMOS camera with an ultra-long scan depth, high resolution and high scan speed exhibited the best overall performance and therefore was recommended for imaging real-time accommodation. |
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 17 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 3 | 18% |
| Student > Postgraduate | 2 | 12% |
| Student > Doctoral Student | 1 | 6% |
| Student > Master | 1 | 6% |
| Unknown | 10 | 59% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 3 | 18% |
| Physics and Astronomy | 2 | 12% |
| Medicine and Dentistry | 2 | 12% |
| Psychology | 1 | 6% |
| Unknown | 9 | 53% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2018.
All research outputs
#20,525,274
of 23,094,276 outputs
Outputs from Eye and Vision
#121
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Outputs of similar age
#286,159
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Outputs of similar age from Eye and Vision
#5
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