| Title |
The Gluten-Free/Casein-Free Diet: A Double-Blind Challenge Trial in Children with Autism
|
|---|---|
| Published in |
Journal of Autism and Developmental Disorders, September 2015
|
| DOI | 10.1007/s10803-015-2564-9 |
| Pubmed ID | |
| Authors |
Susan L. Hyman, Patricia A. Stewart, Jennifer Foley, Usa Cain, Robin Peck, Danielle D. Morris, Hongyue Wang, Tristram Smith |
| Abstract |
To obtain information on the safety and efficacy of the gluten-free/casein-free (GFCF) diet, we placed 14 children with autism, age 3-5 years, on the diet for 4-6 weeks and then conducted a double-blind, placebo-controlled challenge study for 12 weeks while continuing the diet, with a 12-week follow-up. Dietary challenges were delivered via weekly snacks that contained gluten, casein, gluten and casein, or placebo. With nutritional counseling, the diet was safe and well-tolerated. However, dietary challenges did not have statistically significant effects on measures of physiologic functioning, behavior problems, or autism symptoms. Although these findings must be interpreted with caution because of the small sample size, the study does not provide evidence to support general use of the GFCF diet. |
X Demographics
The data shown below were collected from the profiles of 71 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 11 | 15% |
| Spain | 6 | 8% |
| United Kingdom | 6 | 8% |
| Canada | 4 | 6% |
| Saudi Arabia | 2 | 3% |
| Mexico | 2 | 3% |
| Myanmar | 1 | 1% |
| Ireland | 1 | 1% |
| Australia | 1 | 1% |
| Other | 6 | 8% |
| Unknown | 31 | 44% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 50 | 70% |
| Practitioners (doctors, other healthcare professionals) | 10 | 14% |
| Scientists | 8 | 11% |
| Science communicators (journalists, bloggers, editors) | 3 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 304 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Poland | 1 | <1% |
| Denmark | 1 | <1% |
| Unknown | 301 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 65 | 21% |
| Student > Master | 40 | 13% |
| Researcher | 26 | 9% |
| Student > Ph. D. Student | 21 | 7% |
| Student > Doctoral Student | 17 | 6% |
| Other | 52 | 17% |
| Unknown | 83 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Nursing and Health Professions | 50 | 16% |
| Medicine and Dentistry | 44 | 14% |
| Psychology | 29 | 10% |
| Agricultural and Biological Sciences | 23 | 8% |
| Social Sciences | 14 | 5% |
| Other | 47 | 15% |
| Unknown | 97 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 171. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 August 2022.
All research outputs
#240,308
of 25,654,806 outputs
Outputs from Journal of Autism and Developmental Disorders
#52
of 5,484 outputs
Outputs of similar age
#2,893
of 278,579 outputs
Outputs of similar age from Journal of Autism and Developmental Disorders
#3
of 87 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,484 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.4. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,579 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.