Title |
Transcriptomic, lipid, and histological profiles suggest changes in health in fish from a pesticide hot spot
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Published in |
Marine Environmental Research, June 2018
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DOI | 10.1016/j.marenvres.2018.06.020 |
Pubmed ID | |
Authors |
Sharon E. Hook, Julie Mondon, Andrew T. Revill, Paul A. Greenfield, Rachael A. Smith, Ryan D.R. Turner, Patricia A. Corbett, Michael St J. Warne |
Abstract |
Barramundi (Lates calcarifer) were collected at the beginning (1st sampling) and end (2nd sampling) of the wet season from Sandy Creek, an agriculturally impacted catchment in the Mackay Whitsundays region of the Great Barrier Reef catchment area, and from Repulse Creek, located approximately 100 km north in Conway National Park, to assess the impacts of pesticide exposure. Gill and liver histology, lipid class composition in muscle, and the hepatic transcriptome were examined. The first sample of Repulse Creek fish showed little tissue damage and low transcript levels of xenobiotic metabolism enzymes. Sandy Creek fish showed altered transcriptomic patterns, including those that regulate lipid metabolism, xenobiotic metabolism, and immune response; gross histological alterations including lipidosis; and differences in some lipid classes. The second sampling of Repulse Creek fish showed similar alterations in hepatic transcriptome and tissue structure as fish from Sandy Creek. These changes may indicate a decrease in health of pesticide exposed fish. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 73 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 13 | 18% |
Researcher | 9 | 12% |
Student > Ph. D. Student | 8 | 11% |
Student > Doctoral Student | 5 | 7% |
Other | 3 | 4% |
Other | 6 | 8% |
Unknown | 29 | 40% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 15 | 21% |
Environmental Science | 10 | 14% |
Biochemistry, Genetics and Molecular Biology | 3 | 4% |
Veterinary Science and Veterinary Medicine | 2 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Other | 7 | 10% |
Unknown | 34 | 47% |