Title |
Lipid droplet dynamics in budding yeast
|
---|---|
Published in |
Cellular and Molecular Life Sciences, April 2015
|
DOI | 10.1007/s00018-015-1903-5 |
Pubmed ID | |
Authors |
Chao-Wen Wang |
Abstract |
Eukaryotic cells store excess fatty acids as neutral lipids, predominantly triacylglycerols and sterol esters, in organelles termed lipid droplets (LDs) that bulge out from the endoplasmic reticulum. LDs are highly dynamic and contribute to diverse cellular functions. The catabolism of the storage lipids within LDs is channeled to multiple metabolic pathways, providing molecules for energy production, membrane building blocks, and lipid signaling. LDs have been implicated in a number of protein degradation and pathogen infection processes. LDs may be linked to prevalent human metabolic diseases and have marked potential for biofuel production. The knowledge accumulated on LDs in recent years provides a foundation for diverse, and even unexpected, future research. This review focuses on recent advances in LD research, emphasizing the diverse physiological roles of LDs in the model system of budding yeast. |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Sweden | 1 | <1% |
Unknown | 118 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 26 | 22% |
Researcher | 18 | 15% |
Student > Master | 17 | 14% |
Student > Bachelor | 9 | 8% |
Other | 6 | 5% |
Other | 18 | 15% |
Unknown | 25 | 21% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 42 | 35% |
Agricultural and Biological Sciences | 32 | 27% |
Chemical Engineering | 3 | 3% |
Environmental Science | 3 | 3% |
Engineering | 3 | 3% |
Other | 7 | 6% |
Unknown | 29 | 24% |