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Wnt signaling pathways in myocardial infarction and the therapeutic effects of Wnt pathway inhibitors

Overview of attention for article published in Acta Pharmacologica Sinica, July 2018
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Title
Wnt signaling pathways in myocardial infarction and the therapeutic effects of Wnt pathway inhibitors
Published in
Acta Pharmacologica Sinica, July 2018
DOI 10.1038/s41401-018-0060-4
Pubmed ID
Authors

Wen-bin Fu, Wei Eric Wang, Chun-yu Zeng

Abstract

Myocardial infarction (MI) is one of the most serious health threats, resulting in huge physical and economic burdens worldwide. Wnt signaling pathways play an important role in developmental processes such as tissue patterning, cell differentiation and cell division. Appropriate regulation of the activities of Wnt signaling pathways is also important for heart development and healing in post-MI heart. Moreover, Wnt pathway inhibitors have been identified as novel antitumor drugs and applied in ongoing clinical trials. This research progress has generated increasing interests for investigating the effects of Wnt pathway inhibitors on MI healing. In this short review, we summarize the roles of Wnt signaling pathways in post-MI heart and the therapeutic effects of Wnt pathway inhibitors on MI, and discuss the underlying mechanisms of Wnt pathway inhibitors in cardiac repairing.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 71 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 13 18%
Student > Ph. D. Student 12 17%
Student > Bachelor 9 13%
Student > Postgraduate 4 6%
Student > Doctoral Student 2 3%
Other 3 4%
Unknown 28 39%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 23 32%
Medicine and Dentistry 8 11%
Agricultural and Biological Sciences 4 6%
Chemistry 2 3%
Economics, Econometrics and Finance 2 3%
Other 4 6%
Unknown 28 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2018.
All research outputs
#20,527,576
of 23,096,849 outputs
Outputs from Acta Pharmacologica Sinica
#1,390
of 1,622 outputs
Outputs of similar age
#286,370
of 326,948 outputs
Outputs of similar age from Acta Pharmacologica Sinica
#34
of 49 outputs
Altmetric has tracked 23,096,849 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,622 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 326,948 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.