Title |
A Randomized Controlled Trial of Personalized Text Message Reminders to Promote Medication Adherence Among HIV-Positive Adolescents and Young Adults
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Published in |
AIDS and Behavior, September 2015
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DOI | 10.1007/s10461-015-1192-x |
Pubmed ID | |
Authors |
Robert Garofalo, Lisa M. Kuhns, Anna Hotton, Amy Johnson, Abigail Muldoon, Dion Rice |
Abstract |
HIV-positive adolescents and young adults often experience suboptimal medication adherence, yet few interventions to improve adherence in this group have shown evidence of efficacy. We conducted a randomized trial of a two-way, personalized daily text messaging intervention to improve adherence to antiretroviral therapy (ART) among N = 105 poorly adherent HIV-positive adolescents and young adults, ages 16-29. Adherence to ART was assessed via self-reported visual analogue scale (VAS; 0-100 %) at 3 and 6-months for mean adherence level and proportion ≥90 % adherent. The average effect estimate over the 6-month intervention period was significant for ≥90 % adherence (OR = 2.12, 95 % CI 1.01-4.45, p < .05) and maintained at 12-months (6 months post-intervention). Satisfaction scores for the intervention were very high. These results suggest both feasibility and initial efficacy of this approach. Given study limitations, additional testing of this intervention as part of a larger clinical trial with objective and/or clinical outcome measures of adherence is warranted. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 2 | 50% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 2 | <1% |
Sweden | 1 | <1% |
Canada | 1 | <1% |
Unknown | 279 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 49 | 17% |
Researcher | 45 | 16% |
Student > Ph. D. Student | 31 | 11% |
Student > Bachelor | 27 | 10% |
Student > Doctoral Student | 14 | 5% |
Other | 48 | 17% |
Unknown | 69 | 24% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 54 | 19% |
Nursing and Health Professions | 47 | 17% |
Social Sciences | 25 | 9% |
Psychology | 19 | 7% |
Agricultural and Biological Sciences | 10 | 4% |
Other | 40 | 14% |
Unknown | 88 | 31% |