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Plasmonic Nanopores for Trapping, Controlling Displacement, and Sequencing of DNA

Overview of attention for article published in ACS Nano, October 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

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13 X users
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8 patents

Citations

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150 Dimensions

Readers on

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205 Mendeley
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Title
Plasmonic Nanopores for Trapping, Controlling Displacement, and Sequencing of DNA
Published in
ACS Nano, October 2015
DOI 10.1021/acsnano.5b04173
Pubmed ID
Authors

Maxim Belkin, Shu-Han Chao, Magnus P Jonsson, Cees Dekker, Aleksei Aksimentiev

Abstract

With the aim of developing a DNA sequencing methodology, we theoretically examine the feasibility of using nanoplasmonics to control the translocation of a DNA molecule through a solid-state nanopore and to read off sequence information using surface enhanced Raman spectroscopy. Using molecular dynamics simulations, we show that high-intensity optical hot spots produced by a metallic nanostructure can arrest DNA translocation through a solid-state nanopore, thus providing a physical knob for controlling the DNA speed. Switching the plasmonic field on and off can displace the DNA molecule in discrete steps, sequentially exposing neighboring fragments of a DNA molecule to the pore as well as to the plasmonic hot spot. Surface enhanced Raman scattering from the exposed DNA fragments reports on their nucleotide composition, might allow for identification of the nucleotide sequence of a DNA molecule transported through the hot spot. The principles of plasmonic-nanopore sequencing can be extended to detection of DNA modifications and RNA characterization.

X Demographics

X Demographics

The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 205 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 1%
Netherlands 1 <1%
Belgium 1 <1%
United Kingdom 1 <1%
Japan 1 <1%
Spain 1 <1%
Unknown 197 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 57 28%
Researcher 32 16%
Student > Master 26 13%
Student > Bachelor 17 8%
Student > Doctoral Student 11 5%
Other 30 15%
Unknown 32 16%
Readers by discipline Count As %
Physics and Astronomy 49 24%
Engineering 40 20%
Chemistry 38 19%
Materials Science 13 6%
Biochemistry, Genetics and Molecular Biology 9 4%
Other 21 10%
Unknown 35 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 October 2023.
All research outputs
#2,847,161
of 25,810,956 outputs
Outputs from ACS Nano
#2,645
of 15,617 outputs
Outputs of similar age
#37,336
of 287,883 outputs
Outputs of similar age from ACS Nano
#59
of 258 outputs
Altmetric has tracked 25,810,956 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 15,617 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.8. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 287,883 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 258 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.