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Mendeley readers
| Title |
The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extracts
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|---|---|
| Published in |
Food Chemistry, July 2018
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| DOI | 10.1016/j.foodchem.2018.07.154 |
| Pubmed ID | |
| Authors |
Aleksandra Cvetanović, Jaroslava Švarc-Gajić, Zoran Zeković, Jelena Jerković, Gokhan Zengin, Uroš Gašić, Živoslav Tešić, Pavle Mašković, Cristina Soares, M. Fatima Barroso, Cristina Delerue-Matos, Saša Đurović |
| Abstract |
The main goal of this research was to determine the relationship among chemical structure, bioactivity and temperature of chamomile during subcritical water extraction in isobaric conditions (45 bar) at seven different temperatures (65-210 °C). The influence of temperature on phenolic profiles was defined by UHPLC-HESI-MS/MS. The overall results indicate that the presence of conjugated double bonds, side chains, glucose moiety or ether moiety in molecules influence the efficiency of polyphenols' extraction in subcritical water. In terms of antioxidant activity, the extracts were the most active towards ABTS radicals (IC50 = 7.3-16.8 µg/mL), whereby temperature of 150 °C was optimal. On the other hand, the extracts obtained at 115 °C showed highest cytotoxicity. Inhibition of α-amylase and α-glucosidase was the highest at 65 and 85 °C, i.e. 0.51 and 4.13 mmolAE/g, respectively. Activity against tyrosinase was the highest at 210 °C (17.92 mgKAE/g). The data showed that different non-phenolic compounds may also participate in bio-activities of the extracts. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 104 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 104 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 18 | 17% |
| Student > Ph. D. Student | 13 | 13% |
| Researcher | 12 | 12% |
| Student > Bachelor | 10 | 10% |
| Student > Postgraduate | 8 | 8% |
| Other | 10 | 10% |
| Unknown | 33 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 16 | 15% |
| Engineering | 10 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 8 | 8% |
| Chemistry | 8 | 8% |
| Biochemistry, Genetics and Molecular Biology | 6 | 6% |
| Other | 16 | 15% |
| Unknown | 40 | 38% |