| Chapter title |
EBV and Autoimmunity.
|
|---|---|
| Chapter number | 15 |
| Book title |
Epstein Barr Virus Volume 1
|
| Published in |
Current topics in microbiology and immunology, January 2015
|
| DOI | 10.1007/978-3-319-22822-8_15 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-922821-1, 978-3-31-922822-8
|
| Authors |
Ascherio, Alberto, Munger, Kassandra L, Alberto Ascherio, Kassandra L. Munger, Munger, Kassandra L. |
| Abstract |
Although a role of EBV in autoimmunity is biologically plausible and evidence of altered immune responses to EBV is abundant in several autoimmune diseases, inference on causality requires the determination that disease risk is higher in individuals infected with EBV than in those uninfected and that in the latter it increases following EBV infection. This determination has so far been possible only for multiple sclerosis (MS) and, to some extent, for systemic lupus erythematosus (SLE), whereas evidence is either lacking or not supportive for other autoimmune conditions. In this chapter, we present the main epidemiological findings that justify the conclusion that EBV is a component cause of MS and SLE and possible mechanisms underlying these effects. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 108 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 18 | 17% |
| Researcher | 11 | 10% |
| Student > Doctoral Student | 10 | 9% |
| Student > Ph. D. Student | 7 | 6% |
| Student > Postgraduate | 6 | 6% |
| Other | 19 | 18% |
| Unknown | 37 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 27 | 25% |
| Biochemistry, Genetics and Molecular Biology | 11 | 10% |
| Immunology and Microbiology | 7 | 6% |
| Agricultural and Biological Sciences | 5 | 5% |
| Neuroscience | 5 | 5% |
| Other | 10 | 9% |
| Unknown | 43 | 40% |