| Title |
A randomised controlled trial comparing the effects of a 12-week supervised exercise versus usual care on outcomes in haematological cancer patients
|
|---|---|
| Published in |
Supportive Care in Cancer, September 2015
|
| DOI | 10.1007/s00520-015-2955-7 |
| Pubmed ID | |
| Authors |
Bonnie J. Furzer, Timothy R. Ackland, Karen E. Wallman, Anna S. Petterson, Sandy M. Gordon, Kemi E. Wright, David J. L. Joske |
| Abstract |
Following treatment, haematological cancer (HEM) patients exhibit significant physical deconditioning and psychological distress. Exercise has been shown as a clinically effective and safe intervention for cancer patients, with the potential to reverse the deleterious effects following treatment. Our aim was to investigate the efficacy of a 12-week exercise rehabilitation on cancer-related fatigue (CRF) and associated outcomes in HEM patients post-treatment. Patients with a HEM were recruited to participate in a 12-week exercise rehabilitation intervention post-treatment. Pre-, post- and follow-up assessments were conducted on outcome measures including CRF, quality of life (QoL), psychological distress, cardiovascular fitness, muscle strength (MS) and body composition. Patients were given tailored exercise programmes comprising aerobic and resistance exercises, carried out three times per week for 12 weeks in local gyms and clinics. Usual-care participants were offered a delayed, tailored 12-week exercise intervention after the initial study period. Thirty-seven patients (49 % recruitment rate) were randomly assigned to the 12-week exercise rehabilitation (n = 18) or usual care (n = 19) with a 91 % adherence to the exercise intervention. Following the exercise programme, significant improvements were seen in CRF (p = 0.01), cardiovascular fitness (p ≤ 0.001), QoL (p ≤ 0.001), MS (p ≤ 0.001) and body composition (p = 0.001), with moderate to large effects for all primary outcomes. Patient follow-up at 24 weeks demonstrated outcome maintenance in the exercise rehabilitation group and significant improvements in outcomes in usual-care patients following participation in a delayed exercise programme. There were no adverse reactions or study withdrawals. A 12-week exercise rehabilitation programme resulted in significant statistical (p ≤ 0.05) and clinical improvements in CRF and additional outcomes in HEM patients following treatment. Additionally, a 12-week delayed exercise programme showed similar significant improvements in patient outcomes. Australian New Zealand Clinical Trials Registry ACTRN12609000450213. |
X Demographics
The data shown below were collected from the profiles of 32 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 12 | 38% |
| Canada | 2 | 6% |
| Australia | 2 | 6% |
| Portugal | 1 | 3% |
| Luxembourg | 1 | 3% |
| Spain | 1 | 3% |
| France | 1 | 3% |
| Greece | 1 | 3% |
| United States | 1 | 3% |
| Other | 0 | 0% |
| Unknown | 10 | 31% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 19 | 59% |
| Scientists | 9 | 28% |
| Practitioners (doctors, other healthcare professionals) | 4 | 13% |
Mendeley readers
The data shown below were compiled from readership statistics for 172 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | <1% |
| Unknown | 171 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 28 | 16% |
| Student > Bachelor | 25 | 15% |
| Student > Ph. D. Student | 18 | 10% |
| Student > Doctoral Student | 15 | 9% |
| Other | 7 | 4% |
| Other | 23 | 13% |
| Unknown | 56 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Nursing and Health Professions | 34 | 20% |
| Medicine and Dentistry | 24 | 14% |
| Sports and Recreations | 14 | 8% |
| Psychology | 13 | 8% |
| Arts and Humanities | 5 | 3% |
| Other | 21 | 12% |
| Unknown | 61 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 August 2020.
All research outputs
#1,540,578
of 24,364,603 outputs
Outputs from Supportive Care in Cancer
#173
of 4,876 outputs
Outputs of similar age
#21,974
of 279,025 outputs
Outputs of similar age from Supportive Care in Cancer
#4
of 100 outputs
Altmetric has tracked 24,364,603 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,876 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.9. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,025 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 100 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.